温州市艾滋病抗病毒治疗死亡病例流行病学分析  

Epidemiological analysis of AIDS death cases during antiviral therapy in Wenzhou City

作　　者：苏德华[1] 王大勇[1] 叶振淼[1] 赵丽娜[1] 金茜[1] 汪若秋[1] 陈向阳[1] 

机构地区：[1]浙江省温州市疾病预防控制中心艾滋病性病防制所,浙江温州325000

出　　处：《实用预防医学》2015年第5期556-558,共3页Practical Preventive Medicine

基　　金：温州市科技计划项目(编号:Y2014044);温州市医药卫生科技项目(编号:2013B35)

摘　　要：目的分析温州市艾滋病抗病毒治疗死亡病例流行病学特征,为降低病人病死率,提高艾滋病抗病毒治疗效果提供参考依据。方法从国家＂艾滋病综合防治信息系统—抗病毒治疗管理＂数据库收集相关信息,建立Excel数据库并用SPSS17.0软件进行分析。结果全市累计治疗死亡病例94例,男性占86.2%,女性占13.8%,死亡病例平均年龄（55.55±15.27）岁,治疗病死率为7.2%,开始治疗时CD4＋T淋巴细胞≤50个/μl病人病死率为18.0%,CD4＋T淋巴细胞51～200个/μl病人病死率为7.5%,CD4＋T淋巴细胞〉200个/μl病人病死率为2.6%;大部分病例死于艾滋病相关疾病,占总病例的59.6%;在治疗3个月内死亡占54.2%,12个月内死亡的占70.2%。结论温州市艾滋病抗病毒治疗死亡病例治疗时机较晚,应加强病人的早期发现和及时治疗,才能有效地降低病人病死率,提高治疗效果。Objective The aim of the study was to analyze the epidemiological features of AIDS death cases during antiviral therapy in Wenzhou City,so as to reduce the fatality rate of the sufferers and provide references for improving the therapeutic effects of AIDS antiviral treatment. Methods Data were collected from the National AIDS Comprehensive Prevention and Treatment System- the Management of Antivirus Treatment Database,and were analyzed by Excel and SPSS 17. 0. Results A total of 94 AIDS patients died during antiviral therapy. 86. 2% of them were males and 13. 8% were females. Their average age was（ 55. 55 ± 15. 27） years. The treatment fatality rate was 7. 2%. For the groups with CD4＋T cells ≤50 / μl,51- 〉200 / μl and 200 / μl,the fatality rates were 18. 0%,7. 5% and 2. 6% respectively. Most of the patients（ 59. 6%） died of AIDS related diseases. Patients who died within 3 months of treatment accounted for 54. 2%,and those died within 12 months accounted for 70.2%. Conclusions AIDS patients＇ death during antiviral therapy in Wenzhou City is caused by delayed treatment. Early detection and timely treatment should be strengthened to reduce the fatality rate and improve the therapy effect.

关 键 词：艾滋病 抗病毒治疗 死亡 流行病学分析 

分 类 号：R512.91[医药卫生—内科学]