高效液相色谱串联质谱法测定含藻水氯化消毒后7种亚硝胺物质  

Determination of Seven N-Nitrosamines in Eutrophic Drinking Water after Chlorination by High Performance Liquid ChromatographyTandem Mass Spectrometry

作　　者：刘津津[1] 廖晓斌[1] 周真明[1] 李飞[1] 苑宝玲[1] 

机构地区：[1]华侨大学土木工程学院市政与环境工程研究所,厦门361021

出　　处：《分析化学》2015年第4期502-506,共5页Chinese Journal of Analytical Chemistry

基　　金：国家自然科学基金项目(No.51178117);厦门市杰出青年科技人才创新计划项目(No.3502Z20126009)资助~~

摘　　要：采用液相色谱串联质谱法（LC/MS/MS）测定含藻水氯消毒产生7种亚硝胺类（NAms）消毒副产物（NDMA,NMEA,NDEA,NDPA,NDBA,NPyr,NPip）。方法检出限分别为5.0,14,8.6,3.6,2.9,6.3和4.9 ng/L,相关系数r〉0.999。除NDBA回收率（60%）较低外,其余6种亚硝胺回收率均在80%-120%之间,相对标准偏差为1.4%-12.6%。分别以藻原液和消毒后藻液配制基质标准曲线,采用其与纯水标准曲线斜率之比评估基质效应。藻原液的基质效应为0.79-0.94,藻液消毒后NDMA基质效应为0.36,其他亚硝胺为0.63-0.96。应用此方法检测了自来水、富营养江河水、景观水及藻类悬浮液氯消毒后的亚硝胺含量。A method based on solid phase extraction-liquid chromatography-tandem mass spectrometry for determination of 7 nitrosamines（ NAms）（ NDMA,NMEA,NDEA,NDPA,NDBA,NPyr,NPip） in eutrophic drinking water was presented. The detection limits for NAms were 5. 0,14,8. 6,3. 6,2. 9,6. 3and 4. 9 ng / L,respectively,and correlation coefficients for all NAms were over 0. 999. The recoveries ranged from 80% to 120% except NDBA,which was about 60% and RSDs for all NAms were between 1. 4% and12. 6%. Matrix effects were evaluated by the ratio of the slope of matrix-matched and solvent-based calibration curves. The matrix effects in algae suspension ranged from 0. 79 to 0. 94 for 7 NAms,and the range of matrix effects in disinfected algae suspension for other was 0. 63- 0. 96 except NDMA（ 0. 36）. The method was applied to determine nitrosamines in tap water,eutrophic drinking water landscape water and algae suspension after chlorination and chloramination.

关 键 词：高效液相色谱 串联质谱 含藻水 氯 消毒副产物 亚硝胺 

分 类 号：O657.63[理学—分析化学] X832[理学—化学]