超声引导下经腘静脉置管溶栓治疗急性下肢深静脉血栓形成  

Ultrasound guided popliteal vein catheter thrombolysis for acute lower extremity deep venous thrombosis

作　　者：胡潍青[1] 孙波[1] 裴长安[1] 汲武广[1] 曹广信[1] 张杰峰[1] 

机构地区：[1]潍坊市人民医院血管外科,山东省261041

出　　处：《中华普通外科杂志》2015年第4期260-263,共4页Chinese Journal of General Surgery

摘　　要：目的探讨超声引导下经胭静脉置管溶栓治疗急性下肢深静脉血栓形成的可行性及近期疗效。方法回顾性分析2010年4月至2013年4月收治的120例单侧急性下肢深静脉血栓形成患者，其中系统溶栓组60例；导管直接溶栓组60例（2例因穿刺未成功，实际58例）。计算溶栓率和患肢消肿率，作为疗效评价指标，比较2组患者治疗疗效。结果肢体消肿率在系统溶栓组：大腿消肿率为（77±9）％；小腿消肿率为（70±11）％；导管直接溶栓组：大腿消肿率为（87±5）％；小腿消肿率为（80±9）％。2组大小腿消肿率的组间比较，差异均有统计学意义（均P〈0．05）。溶栓率在系统溶栓组为（59±14）％，导管直接溶栓组为（71±13）％。2组比较差异有统计学意义（P〈0．05）。结论超声引导下经胭静脉置管溶栓显著提高了下肢深静脉血栓形成的近期溶栓率。Objective To evaluate the feasibility and efficacy of uhrasound-guided popliteal vein catheter thrombolysis for acute deep venous thrombosis of the lower extremity. Methods Clinical data were retrospectively analyzed on 120 patients of unilateral acute lower extremity deep vein thrombosis from April 2010 to April 2013. 60 cases were included in systemic thrombolytic group; 60 cases into catheter directed thrombolysis group. Tbrombolysis rate and limb swelling reduction rate were calculated and compared between the two groups. Results Due to limb swelling rate, in systemic thrombolysis group： Thigh swelling reduction rate was （77 -＋ 9）% ; Leg swelling reduction rate was （70 ＋ 11 ）%, while in catheter directed thrombolys group, that was （87 _＋ 5 ） %, and （80 ＋ 9） %, respectively （ P 〈 0.05 ）. The thrombolysis rate in systemic group was （59 ＋ 14 ）%, that was （71 ＋ 13 ）% in catheter directed thrombolysis group （P 〈 0. 05 ）. Conclusions Ultrasound guided precutaneous catheter popliteal vein thrombolysis significantly improves the short-term outcome of deep venous thrombosis in terms of leg swelling reduction rate and thrombolysis reduction rate.

关 键 词：静脉血栓形成 血栓溶解疗法 超声检查 介入性 腘静脉 

分 类 号：R543.6[医药卫生—心血管疾病]