两种不同脾栓塞方法临床结果对照研究  

A comparative study of two different methods for partial spleen embolization with clinical outcomes

作　　者：袁莉莉[1] 朱西琪[1] 戴峰[1] 

机构地区：[1]东南大学附属第二医院放射科,江苏南京210003

出　　处：《东南大学学报（医学版）》2015年第2期247-250,共4页Journal of Southeast University(Medical Science Edition)

基　　金：南京市医学科技发展项目(YKK09046)

摘　　要：目的:探讨两种部分脾栓塞方法治疗原发性脾功能亢进的临床疗效。方法:62例肝硬化并发门脉高压及脾功能亢进患者分为外周栓塞组和下极栓塞组,分别行部分性脾栓塞术(PSE)。于术前3 d、术后2周采集外周血,对比两组术前、术后肝功能和外周血象的变化以及并发症的发生情况。结果:两组术前及术后2周比较肝功能无明显变化。两组栓塞术后外周血白细胞、血小板都较术前升高,其中A组较B组效果更为明显,两组差异有统计学意义(P<0.05);A组并发症的发生率大于B组。结论:外周栓塞法比脾脏下极栓塞法缓解脾功能亢进效果更为明显,但相应的并发症也更容易出现,临床实际应用中应权衡选择。Objective： To discuss the clinical outcomes related to portal hypertension of cirrhosis with two different partial splenic embolization（ PSE）. Methods： Sixty- two patients with hypersplenism and portal hypertension complicated with post- hepatic cirrhosis were divided into two groups and received PSE. Liver function,peripheral blood examination were tested regularly pre-PSE and post-PSE,complications were observed.Results： There was no significant changes in liver function of the two groups. Peripheral white blood cells,platelets of two groups all increased than the preoperative after embolization. There were statistically significant difference between the two groups. Those complications included hydrothorax,ascites,left lower pneumonia,and was more serious in group A. Conclusion： The clinical effect of group A is more obvious than group B in hypersplenism treatment,but the corresponding complications are also more likely to report,the clinical applications should be balanced.

关 键 词：肝硬化 门脉高压 脾功能亢进 脾动脉栓塞 

分 类 号：R657.63[医药卫生—外科学]