某型医用多糖止血愈合海绵的阻水和透湿性能研究  

Research on water resistance and moisture permeability of the polysaccharide haemostatic medical sponge

作　　者：徐红霞 乔梅 于燕 王晓阳[2] 王风华 姜毅[2] 

机构地区：[1]海军总医院烧伤整形科,北京100048 [2]海军总医院呼吸内科,北京100048 [3]沈阳军区政治部门诊部 [4]江苏昌吉永生物科技有限公司

出　　处：《中华航海医学与高气压医学杂志》2015年第1期54-55,75,共3页Chinese Journal of Nautical Medicine and Hyperbaric Medicine

摘　　要：目的 研究某型医用多糖止血愈合海绵的阻水、透湿性能.方法 参考国家医药行业标准中的相关规定,取某型医用多糖止血愈合海绵2个型号的辅助敷料各3片,进行500 mm静水压阻水性能实验、水蒸汽透过性能实验,以及整体敷料动物贴敷的防水性能实验.实验动物为健康成年雄性SD大鼠,12只,体质量（185.1 ±27.6）g,按数字表法随机分为淡水组和海水组,每组6只.结果 阻水实验结果表明,300 s后滤纸上没有水渍;水蒸汽透过性能实验表明,水蒸汽接触时辅助敷料的平均水蒸汽透过率为（5 586±373）g/（m^2·24 h）,液体接触时辅助敷料的平均水蒸汽透过率为（11 359±406）g/（m^2· 24 h）;防水性能实验结果表明,淡水组、海水组SD大鼠背部敷料揭开后内部滤纸片干燥,止血成分无吸水表现.结论 该型医用多糖止血愈合海绵辅助敷料的阻水性能及水蒸汽透过性符合医药行业标准,整体敷料具有防水性能.Objective To research water resistance and moisture permeability of the polysaccharide haemostatic medical sponge.Methods With reference to relevant provisions as specified in the national pharmaceutical standards,3 dressings each from the certain type of 2 polysaccharide haemostatic medical sponges were taken for water resistance tests at a hydrostatic pressure of 500 mm,moisture permeability tests,as well as integrated water resistance tests.Results Water resistance tests indicated that there were no stains of water on the filter paper after 300 seconds.Moisture permeability tests showed that average moisture transmission rate was （5 586 ± 373） g/（m^2 · 24 h） when water vapors came into contact with the ancillary dressing,and average water vapor transmission rate was（11 359 ±406）g/（m^2 · 24 h）,when the liquid came into contact with the ancillary dressing.Water resistance tests indicated that the internal filter paper on the back of the rat was dry and water absorption was not clearly visible in the haemostatic material.Conclusions The water resistance and moisture permeability of the ancillary dressing in the polysaccharide haemostatic medical sponge could meet the standards of pharmaceutical industry and it had good water resistance.

关 键 词：医用多糖 止血愈合海绵 阻水性能 水蒸汽透过率 

分 类 号：R318.08[医药卫生—生物医学工程]