移植肾超声造影(CEUS)定量分析的可重复性  

The repeatability of contrast enhanced ultrasound(CEUS)quantitative analysis in assessing transplanted kidney

作　　者：周盛[1] 齐青[1] 何婉媛[1] 季正标[1] 金赟杰[1] 王文平[1] 

机构地区：[1]复旦大学附属中山医院超声科,上海200032

出　　处：《复旦学报（医学版）》2015年第2期212-215,共4页Fudan University Journal of Medical Sciences

基　　金：上海市自然科学基金(13ZR1406400);上海市重点学科建设项目(B112)~~

摘　　要：目的 探讨超声造影定量分析技术在移植肾中的可重复性。方法 54例移植肾患者进行超声造影检查,其中30例移植肾功能正常,24例移植肾急性排斥。两名操作者利用定量分析软件Sonoliver独立对54例移植肾造影资料进行脱机分析,分别在叶间动脉、段间动脉、皮质及髓质区勾画感兴趣区,生成4个ROI的时间强度曲线（time-intense curse,TIC）及其定量参数：上升时间（rising time,RT）、达峰时间（time to peak,TTP）、平均渡越时间（mean transit time,mTT）及拟合优度（quality of fit,QOF）。分析各参数在两名操作者间的一致性。结果段间动脉、叶间动脉、皮质及髓质的RT、TTP、mTT在两名超声研究资质不同的操作者间的组内相关系数（intraclass correlation coefficient,ICC）为0.795~0.954（均〉0.75）,P值均〈0.001。结论 Sonoliver定量分析软件分析移植肾定量参数的一致性较高,可重复性较好。Objective To investigate the repeatability of contrast enhanced ultrasound（CEUS）quantitative softwarein assessing transplanted kidney. Methods Fifty-four patients with transplanted kidney were recruited in the study,including 30 cases with normal transplanted renal function and 24 cases with acute rejection.Two investigators independently analyzed the CEUS videos with quantitative software.Four regions of interest（ROI）including interlobar artery,segmental artery,renal cortex and medulla were drew.For each ROI,time-intense curse（TIC）and the quantitative parameters including rising time（RT）,time to peak（TTP）,mean transit time（mTT）and quality of fit（QOF）were obtained.The consistence of the former three parameters between two investigators was analyzed. Results The intraclass correlation coefficients（ICC）of RT,TTP and mTT of interlobar artery,segmental artery,renal cortex and medulla between the two investigators were all more than 0.75（0.795~0.954）,and Pall〈0.001. Conclusions The consistence of parameters in assessing transplanted kidney with CEUS quantitative software was high.The repeatability of CEUS quantitative analysis between readers with different ultrasound experience was good.

关 键 词：移植肾 超声造影(CEUS) 定量分析 可重复性 

分 类 号：R445.1[医药卫生—影像医学与核医学]