脑钠肽、高敏C反应蛋白、和肽素与急性冠状动脉综合征的相关性  

Correlation of brain natriuretic peptide,high sensitive C reactive protein and peptide with acute coronary syndrome

作　　者：于乐[1] 

机构地区：[1]辽宁中医药大学附属医院心内科,沈阳110032

出　　处：《长春中医药大学学报》2015年第2期398-400,共3页Journal of Changchun University of Chinese Medicine

基　　金：湖南省科技厅基金项目"血管回声跟踪技术评价主动与被动吸烟者大动脉弹性改变的研究"(2010sk3235)

摘　　要：目的探讨脑钠肽(BNP)、和肽素(Copeptin)以及高敏C反应蛋白(CRP)与急性冠状动脉综合征的相关性。方法选取以急性冠脉综合征(ACS)收入院患者72例,随机将患者分成实验1组36例,实验2组36例。记录不同冠脉病变支数患者BNP、CRP以及和肽素水平,冠状动脉Gensini评分。结果患者BNP、和肽素、CRP数据比较,差异具有统计学意义(P<0.01);ACS患者脑钠肽及和肽素水平与冠状动脉病变支数、Gensini评分、左主干病变具有显著正相关性(P<0.01),高敏C反应蛋白水平与冠状动脉病变支数、Gensini评分、左主干病变无显著关系。结论急性冠状动脉综合征患者脑钠肽、和肽素和高敏C反应蛋白显著升高,其表达水平与冠状动脉病变程度具有相关性。Objective To investigate the brain natriuretic peptide（ BNP）,and thepeptide（ Copeptin） and high sensitive C reactive protein（ CRP） associated with acute coronary syndrome. Methods The 72 cases were selected in our hospital with acute coronary syndrome（ ACS）,they were randomly divided into experimental group 1 of 36 cases,36 cases in experimental group 2. Record different coronary lesion vessels in patients with BNP,CRP,and peptide hormone levels,coronary Gensini score. Results Compared the patients with BNP,and peptide,CRP data,the difference was significant（ P〈 0. 01）;to brain natriuretic peptide in patients with ACS and thepeptide hormone level and coronary artery lesions counts,Gensini score,left main coronary artery disease has significant positive association（ P〈 0. 01）,no significant relationship between high sensitivity C reactive level and count,coronary artery lesions of the Gensini score,left main coronary artery diseased（ P〈 0. 05）. Conclusion Patients with acute coronary syndrome of brainnatriuretic peptide and peptide and high sensitive C reactive protein increased significantly,with the correlation of their expression levels and severity of coronary artery lesions.

关 键 词：脑钠肽 和肽素 高敏C反应蛋白 急性冠状动脉综合征 

分 类 号：R446.1[医药卫生—诊断学]