Tf_2NH-catalyzed,highly regio-and stereo-selective synthesis of trisubstituted alkenes and indane derivatives from benzylic alcohols and alkenes  

作　　者：Hai-Hua Li 

机构地区：[1]Department of Environmental and Chemical Engineering,Tangshan College

出　　处：《Chinese Chemical Letters》2015年第3期320-322,共3页中国化学快报（英文版）

摘　　要：A reaction of benzylic alcohols with alkenes has been developed in the presence of bis（trifluoromethane）sulfonimide for the synthesis of trisubstituted alkenes and indane derivatives with high stereoselectivity.In general,benzylic alcohols react with 1,1-diaryl alkenes to afford trisubstituted alkenes,and the reaction with 1,2-disubstituted and trisubstituted alkenes affords indane derivatives through a [3 ＋ 2] annulation reaction.A reaction of benzylic alcohols with alkenes has been developed in the presence of bis（trifluoromethane）sulfonimide for the synthesis of trisubstituted alkenes and indane derivatives with high stereoselectivity.In general,benzylic alcohols react with 1,1-diaryl alkenes to afford trisubstituted alkenes,and the reaction with 1,2-disubstituted and trisubstituted alkenes affords indane derivatives through a [3 ＋ 2] annulation reaction.

关 键 词：alcohols catalyzed afford selectivity stereo Friedel react catalysis inexpensive stilbene 

分 类 号：O621.3[理学—有机化学]