雌孕激素治疗药物流产后阴道出血的效果分析  

Effect of estrogen and progestine for vaginal bleeding after medical abortion

作　　者：柯汝淑 周海慧 张建军 丁香翠[2] 

机构地区：[1]瑞安市妇幼保健院妇产科,浙江温州325200 [2]瑞安市人民医院妇产科,浙江温州325200

出　　处：《中国性科学》2015年第4期11-13,共3页Chinese Journal of Human Sexuality

基　　金：浙江省瑞安市科技计划项目(201302021)

摘　　要：目的:对雌孕激素治疗药物流产后阴道出血的效果展开研究分析。方法:随机选取2011年12月至2013年12月期间我院接收的100例药物流产患者,随机分成研究组和对照组各50例。对照组给予常规抗感染、止血剂治疗,研究组在对照组基础上给予雌孕激素联合治疗,对两组治疗后临床疗效进行观察对比。结果:研究组出血情况,不足月经量30例(60.0%),同等月经量18例(36.0%),超过月经量2例(4.0%);对照组出血情况分别为16例(32.0),22例(44.0),12例(24.0);研究组药物流产后阴道出血显著低于对照组,数据差异具有统计学意义(P<0.05);研究组完全流产50例(100.0%);对照组完全流产35例(70.0%),不完全流产15例(30.0%);研究组完全流产率显著高于对照组,数据差异具有统计学意义(P<0.05);研究组并发症发生率10.0%,对照组并发症发生率40.0%,研究组并发症发生率显著低于对照组,数据差异具有统计学意义(P<0.05)。结论:雌孕激素联合治疗药物流产后阴道出血临床疗效显著,可有效降低阴道出血量,提升完全流产发生率,减少贫血、阴道炎及盆腔炎症等并发症发生,具有临床推广应用价值。Objectives： To study the effect of estrogen and progestin in treating vaginal bleeding after drug abortion. Methods： 100 cases of drug abortion in our hospital from December 2011 to December 2013 were randomly selected and divided into study group and control group,50 cases of each. The control group received conventional anti- inflammatory,haemostatic agent treatment,while study group received additional estrogen and progesterone. The clinical efficacy of the two groups after treatment were observed and compared. Results： In the study group,lack of menstrual flow（ 30 cases,60. 0%）,the same menstrual flow（ 18 cases,36. 0%）,ultra- purchase menstrual flow（ 2 cases,4. 0%）; in the control group,these were 16 cases（ 32. 0%）,22 cases（ 44. 0%） and 12cases（ 24. 0%） respectively; the vaginal bleeding after medical abortion of study group was significantly lower than the control group,with statistically significant difference（ P〈 0. 05）. In the study group,there were 50 cases（ 100. 0%） of complete abortion; in the control group,there were 35 cases（ 70. 0%） of complete abortion and 15cases（ 30. 0%） of incomplete abortion; difference in the rate of complete abortion was statistically significant（ P〈 0. 05）. The incidence of complication in study group was 10. 0%,and 40. 0% in the control group,with statistically significant difference（ P〈 0. 05）. Conclusion： The combination therapy of estrogen and progesterone for vaginal bleeding is of significant clinical effect,which can effectively reduce the amount of vaginal bleeding,elevate the incidence of complete abortion and reduce complications such as anemia,virginities and pelvic inflammatory disorders.

关 键 词：雌孕激素 药物流产 阴道出血 临床疗效 

分 类 号：R167[医药卫生—公共卫生与预防医学]