男性尖锐湿疣患者皮损HPV基因型别的分析  

Analysis of genotypes of human papilloma virus of the male condyloma acuminata patients in Lishui area

作　　者：宁海明[1] 吴绍芳[2] 

机构地区：[1]丽水市人民医院皮肤科,浙江丽水323000 [2]丽水市中心医院皮肤科,浙江丽水323000

出　　处：《中国性科学》2015年第4期71-73,共3页Chinese Journal of Human Sexuality

基　　金：浙江省丽水市科技局公益基金(2012JYZB100)

摘　　要：目的：探讨丽水地区男性尖锐湿疣（CA）患者皮损人乳头瘤病毒（HPV）基因分型情况。方法：采用Hybri Max医用核酸分子快速杂交系统对丽水地区110例男性CA患者的疣体组织样本进行HPV基因分型检测。结果：110例患者中107例HPV检测阳性,HPV感染率97.27%,单一型感染76例,多重感染31例,感染高峰年龄段集中在21-40岁。检测出HPV基因型14种,常见高危型为HPV16、53、52、33、CP8304、58、51、51、68、59;常见低危型为HPV11、6。结论：丽水地区男性CA患者HPV感染以低危型为主,高危型及多重感染率高。Objectives： To explore the genotypes of human papilloma virus（ HPV） of the male condyloma acuminate（ CA） patients in Lishui area. Methods： Through Hybri Max,HPV genotype test was used to detect the genotype of 110 male CA patients in Lishui area. Results： The positive rate of HPV infection was 97. 27% T（ 107）. Among the 110 patients,there were 76 simple infection patients and 31 multiple infection patients. The peak age of infection was from 21 to 40. Totally,14 kinds of HPV genotypes were detected. The common high- risk genotypes were HPV16,53,52,33,CP8304,58,51,68 and 59. The common low- risk genotypes were HPV11 and 6. Conclusion： The low- risk genotype HPV infection is very common in Lishui area,with high rates of high-risk and multiple infections.

关 键 词：尖锐湿疣 男性 乳头瘤病毒 基因型 

分 类 号：R752.53[医药卫生—皮肤病学与性病学]