One-step Synthesis of 5-Ethyl-2-methylpyridine from NH4HCO3 and C2H5OH Under Hydrothermal Condition  

作　　者：TIAN Zhenzhen ZHANG Dong GUO Biao TIAN Ge LIU Xinxin YUE Huijuan FENG Shouhua 

机构地区：[1]State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry [2]Key Laboratory of Physics and Technology for Advance Batteries, Ministry of Education, College of Physics, Jilin University, Changchun 130012, P. R. China

出　　处：《Chemical Research in Chinese Universities》2015年第2期249-252,共4页高等学校化学研究（英文版）

基　　金：Supported by the Natural Science Foundation of Jilin Province, China（No.201215028）, the S＆T Development Program of Jilin Province, China（Nos.20130522128JH, 20140520078JH, 20150204030GX） and the National Natural Science Foundation of China（Nos.21201073, 21401070）.

摘　　要：A simple one-pot approach to synthesizing 5-ethyl-2-methylpyridine（EMP） was established using NHaHCO3 and C2H5OH as starting materials and commercial Cu2O as catalyst and oxidant under hydrothermal con- dition. Different reaction conditions were researched and the optimal ones were achieved by studying the parameters, that could affect the yield of product and by considering the energy and resource saving. The present study provided an eco-friendlv way to obtaining EMP with lower volatility using fewer toxic starting materials.A simple one-pot approach to synthesizing 5-ethyl-2-methylpyridine（EMP） was established using NHaHCO3 and C2H5OH as starting materials and commercial Cu2O as catalyst and oxidant under hydrothermal con- dition. Different reaction conditions were researched and the optimal ones were achieved by studying the parameters, that could affect the yield of product and by considering the energy and resource saving. The present study provided an eco-friendlv way to obtaining EMP with lower volatility using fewer toxic starting materials.

关 键 词：5-Ethyl-2-methylpyridine Hydrothermal condition NH4HCO3 C2H5OH CU2O 

分 类 号：TQ253[化学工程—有机化工] X71[环境科学与工程—环境工程]