新疆2011-2013年梅毒感染孕产妇及所生儿童药物治疗状况及效果分析  

Drug treatment and its effect of syphilis infection in maternal and their children in Xinjiang province during 2011-2013

作　　者：崔丹[1,2] 戴江红[1] 王磊 沙吾力.艾力卡 艾比拜.买买提明 古力帕丽.麦曼提依明 

机构地区：[1]新疆医科大学公共卫生学院,乌鲁木齐830011 [2]新疆维吾尔自治区妇幼保健院,乌鲁木齐830000

出　　处：《中国艾滋病性病》2015年第3期217-219,共3页Chinese Journal of Aids & STD

摘　　要：目的了解新疆梅毒感染孕产妇及其所生儿童的药物治疗现况及其效果。方法利用国家妇幼保健中心提供的预防梅毒母婴传播工作Epidata数据库上报的信息,对梅毒感染孕产及所生儿童规范性治疗和预防性治疗情况和治疗效果进行分析。结果 2011-2013年,新疆梅毒感染孕产妇规范性治疗的总人数为650人,规范治疗率分别是12.81%(31/242)、28.97%(248/856人)、38.17%(371/972),呈逐年上升趋势(χ2=59.523,P<0.001)。2011-2013年梅毒感染孕产妇所生婴儿的预防性治疗总人数为907人,预防性治疗率分别为39.60%(80/202)、43.64%(367/841)和47.92%(460/960),呈逐年上升趋势(χ2=6.229,P=0.013)。截至2013年,梅毒感染产妇所生儿童随访结案的有810例,其中报告先天梅毒儿6例,均为未进行规范治疗的孕产妇所生儿童。结论梅毒感染孕产妇规范治疗率及所生婴儿的预防性治疗率虽逐年在升高,但仍较低,仍有较大的上升空间,梅毒感染孕产妇及所生儿童进行的规范性治疗和预防性治疗,是控制先天梅毒儿发生的有效措施。Objective To investigate the drug treatment status and its effect of syphilis infection in maternal and their children in Xinjiang province. Methods Reported information on prevention of mother-to-child transmission of syphilis infection in Xinjiang province, from EPIDATE database provided by National Center for Women and Children＇s Health, China CDC, was used to analyze the treatment status and its effects of normative and preventive treatment of syphilis infection in maternal and their children. Results The total number of maternal syphilis by normative treatment is 650 in Xinjiang province during 2011-2013, the rate of normative treatment was 12.81% （31/242）, 28.97% （248/856）, 38. 17% （371/972）, respectively, rising year by year （x^2=59.523,P〈0.001）; the total number of infants born to mother with syphilis by preventive treatment is 907 in Xinjiang province during 2011-2013, prophylactic treatment rates were 39.60% （80/202）, 43.64% （367/841） and 47.92% （460/960）, re- spectively, and it had become the rising trend （x^2= 6. 229, P=0. 013） ;there are 810 follow-up cases of children close case by the end of 2013, 6 cases of congenital syphilis were reported, all were the children born to maternal with syphilis without normative treatment. Conclusion Both of the rates of maternal syphilis infection treatment and preventive treatment in infants born to mothers with syphilis were on the rise year by year, but there were still much more upside in the future. Standard treatment and preventive treatment of syphilis infection in maternal and their children are effective measures to control the occurrence of congenital syphilis.

关 键 词：梅毒 孕产妇 规范治疗 先天梅毒 

分 类 号：R759.1[医药卫生—皮肤病学与性病学]