无创呼吸机治疗慢性阻塞性肺疾病合并呼吸衰竭的临床观察  

Clinical Observation of Patients with Chronic Obstructive Pulmonary Disease Complicated with Respiratory Failure to Give Breathing Machine Positive Pressure Ventilation

作　　者：宋威蓉[1] 初巍巍[2] 王莉[3] 

机构地区：[1]沈阳医学院附属第二医院,辽宁沈阳110031 [2]武警辽宁省总队医院 [3]中国医科大学附属第一医院呼吸疾病研究所

出　　处：《中国医学创新》2015年第9期43-45,共3页Medical Innovation of China

基　　金：辽宁省科学技术计划项目(2011414004)

摘　　要：目的:观察无创呼吸机治疗慢性阻塞性肺疾病(COPD)急性加重期合并呼吸衰竭的患者纠正缺氧和改善二氧化碳潴留的临床疗效。方法:选取符合标准的60例慢性阻塞性肺疾病急性加重期合并呼吸衰竭患者为研究对象,对照组20例鼻导管吸氧,研究1组20例COPD急性加重期合并Ⅰ型呼吸衰竭患者无创呼吸机氧疗;研究2组20例COPD急性加重期合并Ⅱ型呼吸衰竭患者无创呼吸机氧疗。观察氧疗前后的Pa O2、Pa CO2水平。结果:研究1组和研究2组的Pa O2经过治疗后明显提高,研究2组Pa CO2经过治疗后明显降低,差异均有统计学意义(P<0.05)。结论:无创呼吸机能有效的纠正慢阻肺急性加重期合并呼吸衰竭患者的缺氧和二氧化碳潴留。Objective：To correct hypoxia and improve the clinical curative effect of carbon dioxide retention of noninvasive ventilator therapy on chronic obstructive pulmonary disease in patients with acute aggravating period of combination of respiratory failure.Method：60 cases of chronic obstructive pulmonary disease in patients with acute aggravating period combination of respiratory failure were selected as the research objects,20 cases when administering oxygen inhalation through nasal catheter were selected as the control group,20 cases of COPD exacerbations mergerⅠtype of respiratory failure patients noninvasive ventilator oxygen therapy were set as research phase 1;20 cases of COPD exacerbations period mergerⅡtype of respiratory failure patients noninvasive ventilator oxygen therapy were set as research phase 2. PaO2,PaCO2 level were observed before and after oxygen cure.Result：1 set of PaO2 and 2 set of PaO2 improved obviously after treatment,the 2 set after treatment PaCO2 decrease were statistically significant（P〈0.05）.Conclusion：Noninvasive respiratory function effective correction of COPD patients with acute aggravating period combination of respiratory failure of oxygen and carbon dioxide retention.

关 键 词：慢性阻塞性肺疾病 无创呼吸机 正压通气 呼吸衰竭 临床观察 

分 类 号：R563.9[医药卫生—呼吸系统]