地佐辛对老年食管癌患者七氟烷麻醉恢复期躁动的影响  

Dezocine on Elderly Patients with Esophageal Cancer Sevoflurane Anesthesia Recovery Restlessness Affect

作　　者：吕帅国[1] 李廷坤[1] 李长生[1] 汪蕾[1] 孙亚林[1] 卢锡华[1] 

机构地区：[1]河南省肿瘤医院麻醉科,河南郑州450013

出　　处：《中国医药指南》2015年第9期19-20,共2页Guide of China Medicine

摘　　要：目的研究地佐辛对老年食管癌根治术患者七氟烷复合麻醉恢复期躁动的影响。方法择期全麻下行食管癌根治术的患者60例,年龄60~75岁,ASA分级Ⅰ或Ⅱ级,随机分为2组（n=30）,生理盐水对照组（C组）和地佐辛（D组）。2组患者静脉注射丙泊酚、芬太尼、顺式阿曲库铵麻醉诱导,吸入2%~3%七氟烷麻醉维持。D组气管插管后静推地佐辛10 mg,C组给予等容量生理盐水。观察术毕躁动的发生率和躁动程度。结果 C组和D组躁动的发生率分别为36.7%和13.3%;与C组比较,D组躁动发生率降低（P〈0.05）。结论地佐辛可降低实施老年食管癌根治术患者七氟烷复合麻醉恢复期躁动的发生率。Objective To investigate the effects of dezocine on postoperative agitation after sevoflurane anesthesia in elderly patients. Methods Sixety ASAⅠ-Ⅱpatients, 60-75 years old, receiving esophageal cancer radical surgery were random Ly divided into two groups（n=30 each）： normal saline control group（group C） and dezocine group（group D）. Anesthesia was induced with propofol, fentanyl and cisatracurium. After propfol induction,patients inhaled 2%-3% sevoflurane for maintenance. In group D 10 mg dezocine were injected intravenously, and group C received the equal volume of normal saline. The incidence and the degree of postoperative agitation, were also recorded. Results Group C and group D patients were restless incidence was 36.7% and 13.3%（P 0.05）. Conclusion Dezocine can reduce the incidence of postanesthetic agitation in elderly patients after sevoflurane anesthesia.

关 键 词：地佐辛 七氟烷 烦躁 麻醉恢复期 

分 类 号：R614[医药卫生—麻醉学] R735.1[医药卫生—外科学]