厦门市低出生体质量儿危险因素病例对照研究  

A case-control study of risk factors for low birth weight infants in Xiamen City

作　　者：伍啸青[1] 陈岚枫 张金华[1] 牛建军[3] 周裕林 谢荣珍[1] 王昊平 陈国伟[1] 蔡黎新 叶曦 李学来 李国伟 

机构地区：[1]福建省厦门市疾病预防控制中心,福建厦门361021 [2]福建医科大学公共卫生学院,福建福州350108 [3]厦门大学附属中山医院,福建厦门361001 [4]福建厦门市妇幼保健院,福建厦门361003 [5]厦门莲花医院,福建厦门361000 [6]福建省湖里区疾病预防控制中心,福建厦门361009 [7]福建省海沧区疾病预防控制中心,福建厦门361026

出　　处：《国外医学（医学地理分册）》2015年第1期36-40,共5页Foreign Medical Sciences：Section of Medgeography

基　　金：福建省科技厅自然科学基金面上项目(No.2012D046);厦门市科技局科技计划项目(No.3502Z20124057);湖里区科技局(No.12社09)

摘　　要：目的探讨厦门市低出生体质量儿的发生及其危险因素,为预防和降低低出生体质量儿的发生提供科学依据。方法采用1∶3配对病例-对照方法,在厦门市属医疗机构收集86例低出生体质量儿及按匹配条件收集258例对照,利用条件Logistic逐步回归模型分析其影响因素。结果母亲文化程度在大专及以上、家庭月人均收入≥4 000元、孕前1年至孕13周内补充叶酸、饮食清淡和产检次数≥5次是保护因素,而妊娠期高血压疾病、孕期服用抗生素、孕周<37周、孕期BMI增幅<5、父亲职业为工人/技术员以及生吃大蒜≥2次/周等是低出生体质量的危险因素。结论厦门地区低出生体质量儿的发生可能由于上述多种原因造成,应采取针对性预防措施降低低出生体质量儿的发生率。Objective To explore the risk factors of low birth weight （LBW）infants in Xiamen City of Fujian Province,and to provide scientific evidence for preventing and reducing the incidence of LBW infants. Methods A 1 ∶ 3 match-control method was used to collect 86 LBW infants and 258 controls according to the matching conditions in Xiamen municipal medical institutions.Influencing factors were analyzed with conditional logistic regression.Results The protective factors of LBW were mother’s educational degree of junior college and above,the average monthly family income 〉 4 000 yuan,intake of folic acid a year before pregnancy to the first three months of pregnancy,balanced diet,and more than 5 times of antenatal examinations.The risk factors of LBW infants included hypertensive disorder complicated with pregnancy,intake of antibiotics,gestational age less than 37 weeks,increase in amplitude of gestational BMI〈5,father was worker or technician,and eating raw garlic more than 2 times per week.Conclusion The above causes may contribute to low birth weight infants in Xiamen City and appropriate preventive measures should be taken to reduce the incidence.

关 键 词：低出生体质量儿 危险因素 病例对照研究 

分 类 号：R179[医药卫生—妇幼卫生保健]