舒正颗粒对糖尿病足介入术后患者疗效的影响  

Shuzheng Granules in Treating Patients with Diabetic Foot after Interventional Therapy

作　　者：曹明满[1] 吕雄[2] 罗仁[1] 江丹[2] 唐慧[2] 莫伟[2] 

机构地区：[1]南方医科大学中医药学院,广东广州510515 [2]广东省第二中医院内分泌科,广东广州510515

出　　处：《南京中医药大学学报》2015年第2期110-113,共4页Journal of Nanjing University of Traditional Chinese Medicine

基　　金：广东省中医药管理局建设中医药强省科研项目(20122165)

摘　　要：目的探讨舒正颗粒对糖尿病足患者介入治疗后疼痛症状、溃疡愈合、下肢供血的影响。方法 ：将糖尿病足行介入治疗成功的患者随机分为舒正颗粒治疗组（22例）和对照组（21例）,2组都给予常规基础治疗,治疗组加用舒正颗粒,观察在疼痛症状积分、溃疡愈合程度、踝肱指数（ABI）、动脉流速、动脉内径方面治疗前后的组内比较和组间比较。结果舒正颗粒治疗组明显改善疼痛症状积分、溃疡深度、溃疡面积、踝肱指数、动脉血流速度、动脉内径、血液流变学等（P〈0.05-0.01）,且优于对照组（P〈0.05-0.01）。结论舒正颗粒联合基础治疗对于促进糖尿病足介入术后患者溃疡愈合、疼痛及下肢供血的改善具有优势。OBJECTIVE To investigate the effect of Shuzheng granules on diabetic foot pain, ulcer healing and lower limb blood supply of the patients with diabetic foot after taking interventional treatment. METHODS Patients with diabetic foot who had taken interventional therapy successfully were randomly divided into Shuzheng granules treatment group（ n = 22） and basic treatment group（ n= 21）. The two groups were given the same regular basic treatment while Shuzheng granules was added to the first group. Then the results including pain symptoms integral, ulcer healing extent, ankle-brachial index（ ABI）, arterial flow velocity and the artery diameter before and after the treatment of the two groups were compared. RESULTS The improvement in pain symptoms integral depth of ulcer, ulcer area, ankle-brachial index, arterial blood flow velocity, arterial diameter and hemarheology were better in the treatment group（ P〈0. 05）. CONCLUSION Shu Zheng granules combined with basic therapy has advantages in ulcer healing, pain relieving and lower limb blood flow increasing for patients with diabetic foot after intervention.

关 键 词：舒正颗粒 介入 糖尿病足 踝肱指数 下肢动脉病变 

分 类 号：R255.4[医药卫生—中医内科学]