急性冠脉综合征患者经皮冠状动脉介入治疗术后低密度脂蛋白胆固醇达标率的影响因素研究  

Influencing Factors of LDL-C Control Rate of Acute Coronary Syndrome Patients Treated by PCI

作　　者：刘波[1] 张磊[1] 崔艳玲[1] 罗东雷[1] 郭靖涛[1] 周江[1] 

机构地区：[1]河北省承德市中心医院心内科,067000

出　　处：《实用心脑肺血管病杂志》2015年第2期13-16,共4页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

摘　　要：目的探讨急性冠脉综合征(ACS)患者经皮冠状动脉介入治疗(PCI)术后低密度脂蛋白胆固醇(LDL-C)达标率的影响因素。方法回顾性分析2002年1月—2013年4月年承德市中心医院收治的900例行PCI的ACS患者的临床资料,分析ACS患者PCI术后1、9个月LDL-C达标情况,并对影响ACS患者PCI术后LDL-C达标率的相关因素进行多因素Logistic回归分析。结果多因素Logistic回归分析结果显示,女性〔OR=0.650,95%CI(0.442,0.956)〕、年龄≥60岁〔OR=0.628,95%CI(0.464,0.850)〕、有高血压病史〔OR=0.737,95%CI(0.547,0.994)〕、既往有心肌梗死病史〔OR=0.696,95%CI(0.511,0.948)〕、既往有PCI史〔OR=0.575,95%CI(0.339,0.974)〕及术前基线LDL-C水平是PCI术后1个月LDL-C达标率的影响因素;既往有心肌梗死病史〔OR=0.706,95%CI(0.521,0.958)〕、既往有PCI史〔OR=0.565,95%CI(0.334,0.957)〕及术前基线LDL-C水平是PCI术后9个月LDL-C达标率的影响因素。结论女性、老年人、高血压、既往有心肌梗死病史、既往有PCI史及基线LDL-C水平较高是ACS患者PCI术后LDL-C达标率的影响因素,对该类患者临床应加强调脂治疗。Objective To investigate influencing factors of LDL-C control rate of acute coronary syndrome（ ACS）patients treated by PCI. Methods Clinical data of 900 ACS patients treated by PCI that admitted to the Central Hospital of Chengde from January 2002 to April 2013 was retrospectively analyzed,and multivariate Logistic regression analysis was used to analyze the influencing factors of LDL-C control rate. Results Multivariate Logistic regression analysis showed that,female〔OR = 0. 650,95% CI（ 0. 442,0. 956） 〕,aged over 60 years old 〔OR = 0. 628,95% CI（ 0. 464,0. 850） 〕,hypertension history 〔OR = 0. 737,95% CI（ 0. 547,0. 994） 〕,myocardial infarction history 〔OR = 0. 696,95% CI（ 0. 511,0. 948） 〕,PCI history 〔OR = 0. 575,95% CI（ 0. 339,0. 974） 〕and baseline LDL-C level were influencing factors of LDL-C control rate after 1 month of PCI（ P〈0. 05）; myocardial infarction history 〔OR = 0. 706,95% CI（ 0. 521,0. 958） 〕,PCI history〔OR = 0. 565,95% CI（ 0. 334,0. 957） 〕and baseline LDL-C level were influencing factors of LDL-C control rate after 9months of PCI（ P〈0. 05）. Conclusion Female,aged,hypertension,myocardial infarction history,PCI history and higher baseline LDL-C level are influencing factors of LDL-C control rate of ACS patients treated by PCI,should strength the lipid lowering treatment.

关 键 词：急性冠脉综合征 血管成形术 气囊 冠状动脉 低密度脂蛋白胆固醇 危险因素 

分 类 号：R542.2[医药卫生—心血管疾病]