广西地区国家规划结核病防治项目疾病分布情况及实验室检测结果分析  

Analysis of tuberculosis distribution and laboratory test results in the region of Guangxi covered by the national tuberculosis control project

作　　者：罗晓璐[1,2] 苏国生[1,2] 黄宛虹 罗顺达 刘泽端[1,2] 

机构地区：[1]广西南宁市第四人民医院检验科 [2]广西艾滋病临床治疗中心

出　　处：《现代预防医学》2015年第8期1492-1494,1515,共4页Modern Preventive Medicine

基　　金：中国全球基金广西结核病项目一期项目(GF-CHN-GXTB-14-11);南宁市重大科技资助项目(201109047C);南宁市科学研究与计划项目资助课题(20123164);广西卫生厅自筹经费项目(Z20120621)

摘　　要：目的了解本地区国家规划结核病防治项目的疾病分布和实验室诊断情况。方法选取2013年1月-2013年11月在某院结核门诊及住院部就诊的国家规划结核病防治项目的病人960人次,观察所有病人的疾病分布情况,并对各项实验室检测指标进行分析,提出相关研究结果。结果在收集的960例病人中,其中男性739例,占76.98%,女性221例,占23.02%,男女患病率比较,其差异有统计学意义,P〈0.05;年龄分布情况,0-20岁28例,21-30岁132例,31-40岁141例,41-50岁168例,51-60岁191例,61-70岁189例,71岁以上139例。从年龄分布看,40岁以下发病率较低,发病例数为273例,占28.44%,40岁以上发病率较高,发病例数687例,占71.56%,2个年龄段比较,差异有统计学意义,P〈0.05;在疾病分布方面,单纯结核病感染731例,占76.14%,结核病合并HIV感染的21例,占2.19%,合并真菌感染196例,占20.42%,结核病合并HIV及真菌感染12例,占1.25%。实验室检测中,有87例肝功能相关指标异常,占9.06%,有192例血常规相关指标异常,占20.00%,合并感染患者的肝功能、血常规相关指标异常指数较单纯感染的高,比较结果差异均有统计学意义,P〈0.05。结论本地区国家规划结核病防治项目病人发病主要以高年龄为主;合并感染患者仍占较高的比例,且其肝功能、血常规相关指标异常指数较单纯感染高,提示临床防治工作应合理检查,综合分析,从而更好地研究治疗方案,以达到最佳的治疗效果。Objective This work was to investigate tuberculosis（TB） distribution and laboratory test results in the region covered by national project of tuberculosis control. Methods 960 tuberculosis outpatients and inpatients of Guangxi Nanning Fourth People＇s Hospital during January 2013 to November 2013 were collected for this study. The disease distribution and tested laboratory indicators were recorded for analysis. Results Among 960 patients, there were 739 males, accounting for 76.98% and 221 females accounting for 23.02%. The prevalence differed significantly with gender（P〈0.05）. The TB distribution with age was 28 cases of 0 to20 years old, 132 cases of 21 to 30 years, 141 cases of 31 to 40 years old, 168 cases of 41 to 50 years, 191 cases of 51 to 60 years old, 189 cases of 61 to 70 years, and 139 cases of over 71 years old. From the age distribution, the incidence among patients below40 years was relatively low, accounting for 28.44% of the total. For the disease distribution, there were 731 cases of TB infection alone, accounting for 76.14%; 21 cases of HIV-TB co-infection, accounting for 2.19%; 196 cases of fungal infection, accounting for20.42%; 12 cases of HIV-TB-fungal co-infection, accounting for 1.25%. By laboratory test, there were 87 cases of abnormal liver function, accounting for 9.06%; 192 cases of blood-related abnormalities, accounting for 20.0%, with higher index values of abnormal liver function and blood abnormality in patients with co-infections than those with single infection. The differences were statistically significant, P〈0.05. Conclusion Among TB patients covered by the national tuberculosis control project, the majority was older than 40 years. The proportion of co-infection patients was relatively high. The indexes of liver- and blood-related abnormalities of patients with co-infection were higher, suggesting that reasonable inspection and comprehensive analysis should be conducted for more efficient treatment and prevention.

关 键 词：国家规划 结核病(TB) 合并感染 HIV 真菌(FV) 

分 类 号：R183.3[医药卫生—流行病学]