糖尿病患者泌尿系感染病原菌分布与耐药性分析  

Pathogens distribution and drug resistance analysis of nosocomial urinary infections in patients with diabetes mellitus

作　　者：于风叶[1] 付洪杰[2] 郭光红[3] 陈贞敏[1] 李敬霞[1] 吴莹[1] 

机构地区：[1]滨州医学院附属医院肾内科,山东滨州256603 [2]滨州医学院附属医院儿科,山东滨州256603 [3]滨州医学院附属医院妇科,山东滨州256603

出　　处：《中华医院感染学杂志》2015年第8期1730-1732,共3页Chinese Journal of Nosocomiology

基　　金：国家自然科学基金资助项目(30571997)

摘　　要：目的研究糖尿病住院患者发生泌尿系感染的病原菌分布特点及药敏分析,为临床治疗提供参考依据。方法收集2012-2014年80例糖尿病住院患者发生泌尿系感染细菌培养及药敏临床资料进行统计分析,数据采用WHO-NET5.4进行统计。结果 80例糖尿病泌尿系感染患者送检尿液标本共检出102株病原菌,以革兰阴性菌为主,共63株占61.8%,其次为革兰阳性菌和真菌,分别占23.5%、14.7%;大肠埃希菌、肺炎克雷伯菌及铜绿假单胞菌对氨苄西林的耐药率分别为95.0%、100.0%、100.0%;粪肠球菌、白色假丝酵母菌、热带假丝酵母菌未发现严重耐药。结论糖尿病患者易发生泌尿系感染,临床应结合药敏试验合理使用抗菌药物。OBJECTIVE To study the pathogen distribution of urinary infections in diabetic inpatients and drug sen- sitive analysis so as to provide reference for clinical treatments. METHODS From 2012 to 2014, the clinical data of bacteria culture and drug sensitivity results of urinary infections in 80 diabetic patients in our hospital were statisti- cally analyzed by WHO-NET 5.4 software. RESULTS In the urine specimens of 80 diabetic patients with urinary tract infections, totally 102 strains of pathogenic bacteria were detected. Gram-negative bacteria with 63 strains dominated the majority, accounting for 61. 8%, followed by gram-positive bacteria and fungi, accounting for 23.5% and 14.7% respectively. The drug resistance rates of Escherichia coli, Klebsiellla pneumonia and Pseud- omonas aeruginosa to ampiciUin were 95.0%, 100.0%, and 100. 0%. Enterococcus faecalis, Candida albicans and Canaida tropicalis were not seriously resistant to any drugs. CONCLUSION Diabetic patients are prone to suffer from urinary tract infections, and antibiotics should be reasonably used according to drug sensitivity test.

关 键 词：糖尿病 泌尿系感染 病原菌 分布 耐药性 

分 类 号：R378[医药卫生—病原生物学]