皮秒脉冲细胞实验装置的设计与仿真优化  

Design and Simulation Optimization of Picosecond Pulsed Cell Experimental Device

作　　者：李成祥[1] 张睿哲[1] 姚陈果[1] 米彦[1] 郭飞[1] 骆阗彦[1] 

机构地区：[1]重庆大学输配电装备及系统安全与新技术国家重点实验室,重庆400030

出　　处：《高电压技术》2015年第4期1365-1371,共7页High Voltage Engineering

基　　金：国家自然科学基金(51307187);重庆市自然科学基金(2011jj A70008)~~

摘　　要：为在相同ps脉冲源输出电压下获得更高的电场强度以进行细胞实验,基于已有研究成果,设计了ps脉冲细胞实验装置,给出了信号不失真传输措施;并采用有限元法和CST建立了细胞实验装置的3维模型,综合考虑ps脉冲信号不失真传输、电场强度足够大以及电场均匀度良好3个重要指标后,对托针和电极池的相关参数进行了仿真优化。结果表明：采用所设计的实验装置传输电磁波时,其反射波幅值较小,并能产生强度较大的电场;托针直径对电极池中的电场分布具有影响,宽托针产生的电场更加均匀、反射波幅值更小;电极池中电场均匀度随极板厚度的减小先增大后减小。根据仿真结果,当托针直径取5 mm、极板厚度在0.66-0.70 mm之间时,电极池中的电场强度足够大且均匀度较好。In order to provide higher electric field intensity for cell experiments at fixed picosecond output voltages, we designed a cell experiment device with picosecond pulse power source based on our previous works and proposed a method for transferring signals without distortion. Then we established a three-dimensional model of the experiment model using CST and finite element methods. Using the model and taking into account three indicators, namely, transferring picosecond pulse without distortion, sufficient electric field intensity and uniform electric field, we simulated and optimized the pin and electrode cuvette of the experiment device. The simulation results indicate that, for electromagnetic waves transferred with the proposed device, they can induce electric field with high intensity while having reflection waves with relatively low amplitude. Diameter of the pin will influence the electric field distribution： increasing the width of pin will enhance the uniformity of electric field and reduce the amplitude of reflection waves. Moreover, the electric field uniformity in electrode cuvette firstly increases and then decreases with decreasing plate thickness. It is concluded that, with pin diameter of 5 mm and plate thickness within 0.66-0.70 mm, the electrode cuvette will have electric field with both enough strength and good uniformity.

关 键 词：ps脉冲 电极池 失真 托针 极板厚度 电场均匀度 

分 类 号：Q274[生物学—细胞生物学]