8种含碳酸盐的矿物类中药的近红外光谱特征谱段分析  

Analysis on NIR characteristic spectral bands of 8 kinds of carbonate mineral traditional Chinese medicines

作　　者：陈龙[1] 袁明洋 余驰 雷咪[1] 陈科力[1] 

机构地区：[1]教育部中药资源和中药复方重点实验室&湖北中医药大学,武汉430065 [2]仙桃市食品药品监督检验所,仙桃433000

出　　处：《药物分析杂志》2015年第4期654-658,共5页Chinese Journal of Pharmaceutical Analysis

基　　金：武汉市2012年高新技术产业发展行动计划生物技术与新医药专项(201260523193)

摘　　要：目的：探讨含碳酸盐的矿物类中药的物相组成,主要成分含量与其近红外光谱特征的相关性,确定含碳酸盐的矿物类中药的近红外光谱特征谱段。方法：采用X衍射法、EDTA滴定法、近红外光谱法对南寒水石、钟乳石、石燕、石蟹、石花、炉甘石、鱼脑石、鹅管石8种含碳酸盐的矿物类中药的物相组成、主成分含量、近红外光谱特征进行分析,探究矿物类中药近红外特征谱段的选择。结果：8种含碳酸盐的矿物类中药的近红外特征谱段中确定6 070~5 000 cm-1和4 800~4 050 cm-1为建模特征谱段,剔除7 350~6 500 cm-1具有合理性。结论：结合X衍射分析结果对近红外光谱特征进行对比分析,可以有效地识别含碳酸盐类矿物类中药的特征谱段,有利于建立合理有效的近红外分析模型。Objective： To explore the correlation between the phase composition and the main components of carbonate mineral traditional Chinese medicines and their near infrared spectrums,and to determine NIR characteristic spectral bands of the carbonate mineral traditional Chinese medicines. Methods： X- ray diffraction method,EDTA titrimetric method and near infrared spectrum（ NIR） were used to determine the phase composition of calcitum,stalactite,stone crab,spirifer,calamine,stone flower,croaker otolith and coral skeleton and to measure contents of their main components,and to compare the characteristics of near infrared spectrums of them so as to explore the appropriate selection of their characteristic spectral bands. Results： It was reasonable to determine the characteristic spectral bands as 6070- 5000 cm- 1and 4800- 4050 cm- 1 for the NIR analysis models,and to exclude the characteristic spectral bands of 7350- 6500 cm- 1. Conclusion： The near infrared spectrums were discussed according to the result of X- ray diffraction,which was effective to identify characteristic spectral bands of mineral traditional Chinese medicines and beneficial to establish reasonable and effective NIR analysis models.

关 键 词：近红外光谱 特征谱段 X衍射分析 物相 矿物类中药 碳酸盐类 南寒水石 钟乳石 石燕 石蟹 石花 炉甘石 鱼脑石 鹅管石 

分 类 号：R917[医药卫生—药物分析学]