藏猪与杜洛克猪血液中胰岛素样生长因子-1、胰岛素样生长因子结合蛋白-3含量差异研究  

Analysis on Differential Content of IGF-1 and IGFBP-3 in Blood of Tibet and Duroc Pigs

作　　者：陶璇[1] 顾以韧[1] 梁艳[1] 杨雪梅[1] 曾凯[1] 陈晓晖[1] 钟志君 杨跃奎[1] 吕学斌[1] 

机构地区：[1]四川省畜牧科学研究院,四川成都610066

出　　处：《养猪》2015年第2期65-67,共3页Swine Production

基　　金：四川省基本科研业务费专项资金(SASA2014A04);国家科技支撑计划(2011BAD28B01-15);国家生猪产业技术体系-综合试验站(CARS-36);优质风味猪配套系选育(2011NZ0099-2);国家现代农业产业技术体系四川创新团队(sccxtd);四川省科技计划项目(2014NZ0092)

摘　　要：为了解国内、外两类猪种肌肉生长发育及血清中相关细胞因子含量差异,以我国特有的藏猪和国外杜洛克猪作为研究对象,采用酶联免疫分析法(ELISA)测定6月龄藏猪、杜洛克猪血清中胰岛素样生长因子-1(IGF-1)、胰岛素样生长因子结合蛋白-3(IGFBP-3)的含量及肌纤维面积(CSA)。结果显示:藏猪血清中IGF-1含量及CSA均极显著低于杜洛克猪(P<0.01),IGFBP-3含量极显著高于杜洛克猪(P<0.01);CSA与IGF-1含量间呈极显著正相关,与IGFBP-3间呈极显著负相关,说明IGF-1对猪背最长肌生长发育有促进作用,而IGFBP-3可能有抑制作用。In this article, Tibet and Duroc pigs were selected to investigating the differences of growing development of muscle and content of correlated cell factors in plasma of domestic and foreign pigs. The content of insulin- like growth factor-1（IGF-1）and insulin-like growth factor binding protein 3 （IGFBP-3） in plasma of Tibet and Duroc pigs of 6 month were menstruated by enzyme-linked immunosorbent assay （ELISA）, cross sectional area of muscle fiber （CSA） of those two pigs were also surveyed. The results showed that the content of IGF-1 in plasma and CSA of Tibet pigs both were significantly lower than Duroc pigs（P〈0.01）, while the content of IGFBP-3 in plasma was significantly higher than Duroc pigs （P〈0.01） . The CSA was significantly positively correlated to IGF-1 content,but significantly negative correlated to IGFBP-3 content.These indicated that IGF-1 can promote growing development of porcine longissimus dorsi, whereas IGFBP-3 may inhibit that.

关 键 词：藏猪 杜洛克猪 胰岛素样生长因子-1 胰岛素样生长因子结合蛋白-3 IGF-1 IGFBP-3 

分 类 号：S828[农业科学—畜牧学]