鲑鱼降钙素和唑来膦酸治疗绝经后骨质疏松症的成本-效果分析  

Cost- effectiveness Analysis of Salmon Calcitonin and Zoledronic Acid in Treating Postmenopausal Osteoporosis

作　　者：白瑶[1] 周学琴[1] 刘玉琴[1] 

机构地区：[1]北京大学深圳医院药剂科,广东深圳518036

出　　处：《黑龙江医学》2015年第3期301-302,共2页Heilongjiang Medical Journal

摘　　要：目的比较鲑鱼降钙素和唑来膦酸治疗绝经后骨质疏松症(PMOP)的成本与效果。方法将126例PMOP患者分为A组和B组,运用药物经济学原理进行成本-效果分析。结果 A组和B组的治疗成本分别为2 279.43元和3 316.79元;总有效率分别为57.14%和79.37%,B组明显高于A组,有统计学差异(P<0.05);经济学方面A组和B组的成本-效果比分别是39.89和41.79。结论应用唑来膦酸治疗绝经后骨质疏松症比鲑鱼降钙素更为合理。Objective To study the cost- effectiveness of calcitonin salmon and zoledronic acid in treating postmenopausal osteoporosis. Methods 126 cases of postmenopausal osteoporosis were collected and randomly divided into two groups： group A and group B. Data was evaluated using the cost- effectiveness analysis of pharmacoeconomics. Results The costs of group A and group B were 2 279. 42 and3 316. 79 yuan respectively. The total effective rates of group A and group B were 57. 14% and 79. 37% respectively. Group B was higher than those in group A,and the difference was statistically significant in two groups（ P〈0. 05）. The cost- effectiveness ratios（ C / E） of group A and group B were 39. 89 and 41. 78 respectively. Conclusion Group B has better compliance and is more reasonable as compared with group A.

关 键 词：鲑鱼降钙素 唑来膦酸 绝经后骨质疏松症 成本-效果分析 

分 类 号：R580[医药卫生—内分泌]