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作 者:崔碧云[1]
机构地区:[1]南方医科大学附属中山市博爱医院儿童哮喘免疫中心儿科,广东中山528403
出 处:《黑龙江医学》2015年第3期324-326,共3页Heilongjiang Medical Journal
摘 要:目的探讨儿童哮喘标准化特异性免疫治疗的安全性,以及护理干预对减少不良反应发生的效果。方法选取260例支气管哮喘患儿接受标准化屋尘螨变应原疫苗特异性免疫治疗。将其随机分为护理干预组与常规护理组,每组各130例,分别予以了4230次治疗。观察并分析两组不良反应情况。结果常规护理组发生了148次不良反应(占3.50%),护理干预组则发生112次不良反应(占2.65%),差异具有统计学意义(P<0.05)。两组不良反应主要发生在剂量递增阶段,但几乎以局部反应为主,全身不良反应情况少。结论标准化特异性免疫对儿童哮喘治疗的安全性较高,通过有效的护理干预,能进一步减少不良反应的发生,提高治疗的安全性和有效性。Objective To discuss safety of the specific immune therapy of childhood asthma standardization,as well as the effect of nursing intervention to reduce adverse reactions occurrence. Methods Selecting 260 cases of childhood with asthma standardized house dust mites allergic source preparation specific immune therapy,and randomly dividing them into treatment group( nursing intervention group) and control group( routine nursing group),with 130 cases in each group. 4230 times treatment was given respectively. Adverse reaction conditions were observed and analyzed. Results Routine nursing group had 148 times of adverse reactions( 3. 50%),and the nursing intervention group had 112 times of adverse reactions( 2. 65%),with statistically significant difference( P〈0. 05). Adverse reactions of two groups mainly occurred in the maintenance treatment stage,but almost were given priority to with local reactions,and systemic adverse reaction was less. Conclusion Standardized high specificity immune has high security of childhood asthma treatment. Through effective nursing intervention,the occurrence of adverse reactions can further be reduced,and the safety and efficacy of treatment be improved.
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