医用纱布蒸汽灭菌验证  

Steam Sterilization of Medical Gauze Sponges

作　　者：邓晓东[1] 吕健[1] 夏唯[1] 杨峰[1] 丁健[1] 

机构地区：[1]广州军区武汉总医院消毒供应科,湖北武汉430070

出　　处：《华南国防医学杂志》2014年第7期704-707,共4页Military Medical Journal of South China

基　　金：中华医院感染控制研究基金项目(ZHYY2013-001)

摘　　要：目的阐述了医用纱布蒸汽灭菌的原理、影响因素、验证方法和无菌保证系统。方法结合蒸汽灭菌理论及生产实践来论证用蒸汽来灭菌纱布产品所需关注的要素,形成综合的灭菌理论。结果蒸汽灭菌的三大基本要素是作用时间、灭菌温度和饱和蒸汽;为确保饱和蒸汽的质量(不冷凝气体,过热相和蒸汽干度),蒸汽源、蒸汽传输系统和灭菌设备都必须有系统的设计和专业的施工;蒸汽灭菌验证一般使用生物指示剂来评估灭菌工艺的无菌保障水平;无菌保障系统是持续维持无菌保证水平的必要条件。结论控制住蒸汽灭菌的三大要素,做好灭菌验证,建立无菌保障系统,可以确保蒸汽灭菌的质量,为使用者提供安全和可靠的产品。Objective Comprehensive exposition of the principles of steam Sterilization of medical gauze, influencing factors,validation Methods and Sterility Assurance System（SAS）.Methods Demonstrate the major factors for steam sterilization by analyzing sterilization theory and sterilization practice to form a comprehensive sterilization theory. Results Three basic elements for steam sterilization are action Time, temperature and saturated steam.Steam source, steam sterilizer and transmission systems must be well designed in Order to assure saturated steam quality（non-condensing gas, superheat and dryness） ;Sterilization process validation Methods commonly Use biological indicators（BI） todemonstrate The Sterility Assurance level （SAL） ;SAS is the key to maintain SAL.Conclusion Well control the influencing factors for sterilization , rightly perform sterilization validation,and establish SAS to assure the sterility of medical gauze sponges so as to provide safe and reliable product for users.

关 键 词：蒸汽灭菌 影响因素 灭菌验证 无菌保障系统 

分 类 号：R521.7[医药卫生—内科学]