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机构地区:[1]廊坊市妇幼保健中心儿童保健科,河北廊坊065000 [2]廊坊市妇幼保健中心超声科,河北廊坊065000
出 处:《华南国防医学杂志》2014年第10期985-987,共3页Military Medical Journal of South China
摘 要:目的充分利用廊坊市妇幼保健信息系统平台,提高对儿童先天性心脏病(congenital heart disease,CHD)的筛查质量,分析研究本地区儿童CHD发病率及影响因素,为当地政府决策提供可靠依据。方法采用望诊、听诊和彩色多普勒超声心动图相结合的方法对辖区内儿童进行监测。对确诊阳性患儿采用1∶2配对的病例对照研究方法、通过单因素分析和多因素条件logistic回归分析逐步筛选危险因素。结果廊坊市儿童CHD发病率为2.299%,其中孕早期感冒(OR=4.983)、妊娠合并症(OR=5.32)、孕早期情绪状况(OR=7.9)、孕早期接触农药(OR=7.812)、孕期被动吸烟(OR=5.23)是危险因素,孕前检查(OR=0.167)、孕期服用多种维生素(OR=0.033)是保护因素。结论母亲孕早期感冒、情绪差、接触农药、妊娠合并症、被动吸烟可增加新生儿患CHD的危险,而母亲孕前检查、及孕早期服用多种维生素则可以降低婴儿患CHD的危险。Objective To make full use of Langfang child health service network,improve the screening quality of children with congenital heart disease(CHD),analyse the risk and influential factors,and supply a reliable reference for the decision of the government.Methods The inspection,auscultation and color Doppler ultrasound Heartbeat map method were utilized to monitor the health condition of the children in the local area.The positive cases were studied with1∶2case-control ratio through the single factor analysis and multivariate conditional logistic regression analysis.Results The incidence of congenital heart disease of children in Langfang was 2.299%.The common cold during pregnancy(OR=4.983),pregnancy complications(OR=5.32),early pregnancy mood status(OR=7.9),while exposure to pesticides during earuy pregrancy(OR=7.812)and passive smoking during pregnancy(OR=5.23)were the risk factors,prepregnancy check(OR=0.167),prenatal multivitamin supplement(OR=0.033)were the protective factors.ConclusionMother's catching cold during early pregnancy,poor mood,pesticide contact,pregnancy complication,and passive smoking can increase the risk of neonatal congenital heart disease,and maternal pre-pregnancy check and vitamin supplement during early pregnancy can reduce the risk.
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