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作 者:王纯巍[1] 伦立德[2] 周平[1] 熊敏[3] 高卓[2]
机构地区:[1]空军总医院感染内科,北京100142 [2]空军总医院风湿肾病科,北京100142 [3]空军总医院中心实验室,北京100142
出 处:《华南国防医学杂志》2014年第10期1024-1025,1028,共3页Military Medical Journal of South China
摘 要:目的分析系统性红斑狼疮患者支原体感染的流行病学特点。方法对110名系统性红斑狼疮患者的眼睑、咽部、尿道分泌物及静脉血标本,应用嵌套式聚合酶链反应,检测人支原体、解脲脲原体和发酵支原体。结果 63.6%系统性红斑狼疮患者存在支原体感染(χ2=26.3,P<0.01),25.4%患者有2个部位感染支原体,9.1%患者有3个部位感染支原体。20.0%患者咽部有人支原体感染(χ2=5.25,P<0.05),22.7%患者尿道有解脲脲原体感染(χ2=6.31,P<0.05)。结论系统性红斑狼疮患者多部位存在支原体感染,支原体感染者患系统性红斑狼疮的危险是未感染者的22倍。Objective To analyze the epidemiological condition of Mycoplasma infection in patients with systemic lupus erythematosus.Methods Mycoplasma hominis,Ureaplasma urealyticum,and Mycoplasma fermentans were detected by nested polymerase chain reaction in eyelid,throat,urethral secretions and blood samples of 110 patients with systemic lupus erythematosus.Results 63.6% of patients with systemic lupus erythematosus showed the Mycoplasma infection at one or more sites(χ2=26.3,P〈0.01),in which25.4% of patients showed the Mycoplasma infection at two sites and 9.1% at three sites.20.0% of patients with systemic lupus erythematosus showed the Mycoplasma hominis infection in the throeat(χ2=5.25,P〈0.05),and 22.7% of patients with systemic lupus erythematosus showed the Ureaplasma urealyticum infection in the urethra(χ2=6.31,P〈0.05).Conclusion Patients with systemic lupus erythematosus have Mycoplasmas infection in several sites.The risk of contracting systemic lupus erythematosus for the subjects infected with Mycoplasmas is 22 times that of those without infection.
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