疏风解毒胶囊治疗老年社区获得性肺炎患者的疗效评价  

Effect Evaluation for Shufeng Jiedu Capsule in the Treatment of the Elderly Patients with Community-acquired Pneumonia

作　　者：张连国[1] 滕国杰[1] 周玉涛[1] 

机构地区：[1]首都医科大学宣武医院呼吸科,北京100053

出　　处：《中国医药导刊》2014年第12期1471-1472,1474,共3页Chinese Journal of Medicinal Guide

摘　　要：目的:评价疏风解毒胶囊治疗老年社区获得性肺炎(community acquired pneumonia,CAP)的临床疗效及安全性。方法:将100例老年CAP病人入院随机分成治疗组与对照组。治疗组病人予莫西沙星静滴,0.4g/d,连续7日,同时予疏风解毒胶囊口服,每次4粒,每日3次,连续7日;对照组予莫西沙星静脉滴注,0.4g/d,连续7日。观察两组病人治疗前后主要临床症状、体征、感染性相关指标、胸片DR变化情况,并评定病人临床治疗效果、不良反应发生情况。结果:与对照组比较,治疗组主要临床症状、体征恢复时间明显缩短(P<0.05),退热疗效尤其显著(P<0.01),而且血白细胞、中性粒细胞比例、C反应蛋白及降钙素原等感染性指标在治疗后第3日显著降低(P<0.05,P<0.01),第7日基本恢复正常;胸部DR提示治疗组炎症病灶完全吸收率明显高于对照组(P<0.05);治疗组总有效率明显高于对照组(P<O.05)。两组均未见严重不良反应发生。结论:疏风解毒胶囊联合莫西沙星治疗能促进老年CAP病人临床症状的改善,加速病人恢复。Objective： To evaluate shufeng jiedu capsule（SFJDC） in the treatment of the elderly patients with community-acquired pneumonia（CAP） of clinical curative effect and security.Methods： 100 elderly inpatients with CAP were randomly divided into treatment group and control group.Treatment group with moxifloxacin, 0.4 g/d, meanwhile, taking SFJDC 4 pills, 3 times a day, for 7 days; control group with moxifloxacin, 0.4 g/d, for 7 days.Then, Observed the change of all of the patients＇ clinical performance, infectious related indicators and DR after treatment, and assessed the clinical curative effect and adverse reactions. Results： Major clinical symptoms and signs of recovery time of treatment group less than control group（P〈0.05）, especially in defervescence（P〈0.01）; the proportion of blood leukocytes and neutrophils, c-reactive protein and procalcitonin after 3 days for treatment group decreased significantly（P〈0.05, P〈0.01）, the 7th to generally normal; inflammatory lesions absorption to treatment group was obviously faster than that of control group compared by DR（P〈0.05）; the total curative effect for treatment group was higher than that of control group（P〈0.05）.There were no serious adverse reactions in the two groups.Conclusion： SFJDC with moxifloxacin can promote the improvement of the clinical symptoms of old patients with CAP, and accelerate the patient＇s recovery.

关 键 词：疏风解毒胶囊 老年患者 社区获得性肺炎 疗效评价 

分 类 号：R563.19[医药卫生—呼吸系统]