一种含氟pH值响应性聚合物的制备  

A Kind of Fluorine Containing pH Responsive Polymer Preparation

作　　者：孙崇彬 张书香[1] 李义滨 

机构地区：[1]济南大学化学化工学院,山东济南250022

出　　处：《山东化工》2015年第8期6-8,共3页Shandong Chemical Industry

基　　金：国家国际科技合作专项子项目(2012DFA70870-3)

摘　　要：通过无皂乳液聚合制备了一种具有p H值响应型的聚合物Poly(TFEMA-DMAEMA-PEGMA),通过红外、核磁、测定了聚合物的结构。通过激光粒度仪和Zeta电位仪测定了聚合物胶束在不同的pH值的磷酸盐缓冲溶液中响应行为,该聚合物可能用于在不同p H值中药物释放载体。A kind of pH - responsive （ DMAEMA - TFEMA - PEGMA） were prepared via surfactam - free emulsion polymerization. The chemical structure of the copolymers was characterized by Fr- IR, NMR. The particles were studied by dynamic light scattering, and zeta potential measurement ; the polymer displayed a significant pH - responsive behavior. This study suggests that the poly （DMAEMA- TFEMA- PEGMA） have potential applications as a-ntrolled drug release carrier.

关 键 词：pH值响应性 甲基丙烯酸二甲基氨乙酯 甲基丙烯酸三氟乙酯 

分 类 号：O632.3[理学—高分子化学]