簇花清风藤脂溶性成分的GC-MS分析  

GC-MS analysis of liposoluble components in Sabia fasciculata Lecomte ex L. Chen

作　　者：郑金燕[1,2] 黄艳[2] 林霄[2] 张春来[1] 刘布鸣[2] 刘元[2] 宋志钊[2] 

机构地区：[1]广西中医药大学,广西南宁530001 [2]广西中药质量标准研究重点实验室广西中医药研究院,广西南宁530022

出　　处：《药学研究》2015年第4期195-198,共4页Journal of Pharmaceutical Research

基　　金：广西科技攻关重大专项(No.桂科重1355001-4);广西科技攻关项目(No.桂科攻11107010-3-4)

摘　　要：目的分析簇花清风藤的脂溶性化学成分。方法采用硅胶柱层析法提取分离簇花清风藤石油醚部位的脂溶性成分,并对该脂溶性成分进行甲酯化处理,采用气相色谱-质谱方法分析其化学成分。结果样品1共鉴定出39个化学成分,主要成分为:(Z)-9-十八烷烯酸(13.15%)、10,12-十八碳二烯酸(6.74%)、棕榈酸(3.94%)、硬脂酸(3.04%)、(Z)-13-二十二碳烯酸(2.76%)、十氢化-8α-乙基-1,1,4α,6-四甲基萘(2.43%)等。样品2共鉴定出10个化学成分,主要成分为:十四酸(4.63%)、15-甲基十六烷酸(4.55%)、14-甲基十五烷酸(4.33%)、叶绿醇(3.09%)等。结论研究结果可为进一步确定簇花清风藤的化学成分和研究利用提供了一定的参考。Objective To analyze the liposoluble components from the Sabia fasciculata Lecomete ex L. Chen. Methods Liposoluble components were extracted from Sabia fasciculata Lecomete ex L. Chen by silica gel column chromatography. The relative contents were determined by GC-MS with area normalization method. Results 39 componts were separated from sample 1. The main ingredients were（Z）-9-octadecenoic acid（13. 15%）;10-trans,12-cis-octadecadienoic acid（6. 74%）;Hexadecanoic acid（3. 94%）;Stearic acid（3. 04%）（;Z）-13-docosenoic acid（2. 76%）;Decahydro-8α-ethyl-1,1,4α,6-tetramethylnaphthalene（2. 43%）in the sample 1. 10 components were separated from sample 2,the main ingre-dients were myristic acid（4. 63%）;15-methyl-hexadecanoic acid（4. 55%）;14-methyl-pentadecanoic acid（4. 33%）;Phytol（3. 09%）. Conclusion The results provided supplements and references for the further utilization and study of the plant of Sabia fasciculata Lecomete ex L. Chen.

关 键 词：簇花清风藤 脂溶性成分 成分分析 气-质联用 

分 类 号：R284.1[医药卫生—中药学]