湿润后米索前列醇联合双异丙酚在无痛人工流产术中的临床效果分析  

Analysis on clinical effect of wet misoprostol combined with dipropofol in painless artificial abortion

作　　者：王菊 

机构地区：[1]广东省深圳市光明新区人民医院妇产科,518106

出　　处：《中国妇幼保健》2015年第13期2052-2053,共2页Maternal and Child Health Care of China

基　　金：广东省深圳市宝安区科技局立项〔2014248〕

摘　　要：目的:探讨湿润后米索前列醇联合双异丙酚在无痛人工流产术中的临床效果。方法:选择接受早期无痛人工流产手术的120例早孕妇女随机分为观察组和对照组各60例,观察组和对照组在术前30 min静脉注射双异丙酚,观察组给予阴道后穹窿放置湿润后米索前列醇400μg,对照组给予常规阴道后穹窿放置米索前列醇片400μg,观察两组的宫颈松弛情况、子宫收缩情况、术中出血量、手术时间等。结果:观察组宫颈松弛情况、子宫收缩情况、术中出血量、手术时间均显著优于对照组,差异有统计学意义(P<0.05)。结论:湿润后米索前列醇和双异丙酚在无痛人工流产术前的联合应用可促进宫颈扩张、增强子宫收缩、术中出血显著减少,有效提高手术质量并减少手术并发症,具有良好的推广应用价值。Objective： To explore the clinical effect of wet misoprostol combined with dipropefol in painless artificial abortion. Methods： A total of early pregnant women receiving early painless artificial abortion were randomly divided into observation group and con- trol group, 60 cases in each group ; the cases in observation group and control group were treated with intravenous injection of dipropofol at 30 minutes before operation, then the cases in observation group were treated with vaginal fornix administration of wet misoprostol （400 μg）, while the cases in control group were treated with vaginal fornix administration of misoprostol （400 μg） .The cervical relaxation and uterine contraction conditions, the amounts of intraoperative blood loss, and operative time in the two groups were observed. Results： The cervical relaxation and uterine contraction conditions, the amount of intraoperative blood loss, and operative time in observation group were statistical- ly significantly better than those in control group （P〈0. 05） . Conclusion： Joint application of wet misoprostol and dipropofol for painless artificial abortion can promote cervical dilation, strengthen uterine contraction, significantly reduce intraoperative bleeding, effectively improve the quality of surgery, and reduce complications, which has good application value.

关 键 词：湿润后米索前列醇 双异丙酚 无痛人工流产 

分 类 号：R714.21[医药卫生—妇产科学]