慢性乙型肝炎患者血清铁蛋白检测在判断肝脏受损中的临床应用  

Clinical significance of measuring serum ferritin level in patients with chronic hepatitis B

作　　者：曹寒沁[1] 

机构地区：[1]浙江大学医学院附属第一医院检验科,浙江杭州310003

出　　处：《实验与检验医学》2015年第2期154-155,共2页Experimental and Laboratory Medicine

基　　金：浙江省医药卫生科技计划项目(编号:2011KYA058)

摘　　要：目的通过对慢性乙型肝炎患者血清铁蛋白的检测,探讨血清铁蛋白含量与肝脏受损之间的关系。方法选取2014年4月至9月在浙江大学医学院附属第一医院感染科住院的慢乙肝患者48例。另外选取40例肝功能正常的健康体检者作为健康对照组,收集基本资料同时检测两组血清铁蛋白水平进行比较分析。结果慢乙肝患者血清铁蛋白水平明显高于健康对照组(P<0.01),且与丙氨酸氨基转移酶呈正相关性(r=0.528,P<0.001)。结论血清铁蛋白可作为肝脏受损的重要参考指标,对于判断病情、了解预后有着重要意义。Objective To explore the relationship between the level of serum ferritin （SF） and liver damage by mesuring SF in patients with chronic hepatitis B （CHB）. Methods Forty-eight CHB patients who hospitalized in the infectious department of the first affiliated hospital of Zhejiang university＇s Medical college from April to September in 2014 were enrolled in our study. In addition, 40 healthy check-up person with normal liver function were selected as healthy controls （HCs）. At the same time, the basic data were collected and compared. Results The SF level of CHB patients significantly higher than HCs（P〈0.01）. There was significant positive correlation between SF and alanine transaminase （ALT） （r=0.528, P〈0.001）. Conclusion SF may be served as an important reference index for liver damage, and with important significance in judging the condition and prognosis of CHB patients.

关 键 词：慢性乙型肝炎 血清铁蛋白 肝脏受损 

分 类 号：R512.6[医药卫生—内科学] R446.112[医药卫生—临床医学]