泰山白首乌的化学成分研究  

Chemical Constituents of Roots of Cynanchum Bungei Decne

作　　者：孙得峰[1,2] 孙敬勇[1,2] 郑重飞[3] 李莹[1,2] 姚庆强[1,2] 

机构地区：[1]山东省医学科学院药物研究所 [2]济南大学/山东省医学科学院医学与生命科学学院山东省罕少见病重点实验室,山东济南250062 [3]中国人民解放军456医院,山东济南250031

出　　处：《食品与药品》2015年第2期90-93,共4页Food and Drug

摘　　要：目的研究泰山白首乌块根的化学成分。方法采用多种分离技术分离纯化化合物,根据理化性质,采用现代波谱技术进行结构鉴定。结果从泰山白首乌块根中分离得到12种化合物,分别鉴定为:白首乌乙素(Ⅰ),白首乌二苯酮(Ⅱ),戟叶牛皮消苷-C(Ⅲ),2,5-二羟基苯乙酮(Ⅳ),3-羟基苯乙酮(Ⅴ),4-羟基苯乙酮(Ⅵ),白桦脂酸(Ⅶ),2,4-二羟基苯乙酮(Ⅷ),β-谷甾醇(Ⅸ),琥珀酸(Ⅹ),胡萝卜苷(Ⅺ),对苯二酚(Ⅻ)。结论化合物Ⅴ为首次从该属植物中分离得到。Objective To investigate the chemical constituents in the roots of Cynanchum bungei Decne..Methods The chemical constituents were isolated by a variety of separation technology,and their structures were identified by spectral analysis,on the basis of physiochemical properties.Results 12 compounds were isolated and identified as： 2,6,2＇-trihydroxy-3-acetyl-4＇-（2＇＇,6＇＇-dihydroxy-3＇＇-acetyl） phenyl-6＇-methyl-benzophenone（Ⅰ）,baishouwuhenzophenone（Ⅱ）,bungeiside-C（Ⅲ）,2,5-dihydroxyacetophenone（Ⅳ）,3＇-hydroxyacetophenone（Ⅴ）,4＇-hydroxyacetophenone（Ⅵ）,betulonicacid（Ⅶ）,2,4-dihydroxyacetophenone（Ⅷ）,β-sitosterol（Ⅸ）,succinic acid（Ⅹ）,eleutheroside A（Ⅺ）,hydroquinone（Ⅻ）.Conclusion Of all the compounds above,3＇-hydroxyacetophenone（Ⅴ） was delaminated from Cynanchum bungei Decne.for the first time.

关 键 词：泰山白首乌 化学成分 

分 类 号：R284[医药卫生—中药学]