麦粒灸对肿瘤患者生活质量及其外周血中IL-10表达的影响  

Effect of Wheat-sized Moxibustion on the Quality of Life and IL-10 in Peripheral Blood of Patients with Tumor

作　　者：付铃 万茜[2] 徐天舒[2] 

机构地区：[1]南京中医药大学中西医结合鼓楼临床学院,南京210029 [2]南京市鼓楼医院,南京210000

出　　处：《上海针灸杂志》2015年第4期305-309,共5页Shanghai Journal of Acupuncture and Moxibustion

基　　金：南京市医学科技发展课题(2013)

摘　　要：目的通过对临床肿瘤Ⅲ~Ⅳ期患者QLQ-C30生活量表与对照组比较来观察施用麦粒灸治疗后两组不同中医证型患者生活质量的不同及其IL-10表达的差异,以此来探寻在肿瘤Ⅲ~Ⅳ期治疗中麦粒灸的治疗是否能改善患者的生活质量,调节肿瘤相关免疫,提高带瘤生存率。方法将42例肿瘤患者随机分为治疗组和对照组,并进行中医辨证分型,治疗组在常规中西医结合治疗的基础上加用2星期麦粒灸治疗,对两组患者治疗前及治疗后分别进行QLQ-C30生活量表评分,并留取外周血标本进行IL-10检测。结果麦粒灸治疗能改善患者生活质量,尤其以乏力及纳差改善明显;麦粒灸治疗后IL-10的表达较治疗前有所下降。结论麦粒灸能改善肿瘤患者生存质量,下调IL-10的表达。Objective By observing and comparing the effect of wheat-sized moxibustion on the quality of life and interleukin（IL）-10 expression in stage Ⅲ~Ⅳ tumor patients of two different traditional Chinese medicine（TCM） patterns by using QLQ-C30 questionnaire, to see whether wheat-sized moxibustion can improve the quality of life, regulate oncology-related immune system, and enhance the survival rate of the stage Ⅲ~Ⅳ tumor patients. Method Forty-two tumor patients were randomized into a treatment group and a control group and were differentiated into TCM patterns. The treatment group was intervened by conventional Chinese and Western medicine plus 2 weeks of wheat-sized moxibustion. QLQ-C30 questionnaire was adopted for evaluation before and after treatment, and peripheral blood was drawn to detect the expression of IL-10. Result Wheat-sized moxibustion improved the quality of life, especially fatigue and poor appetite; the expression of IL-10 dropped after wheat-sized moxibustion. Conclusion Wheat-sized moxibustion can improve the quality of life of the tumor patients and down-regulate the expression of IL-10.

关 键 词：肿瘤 麦粒灸疗法 QLQ-C30生活量表 IL-10 灸法 

分 类 号：R246.1[医药卫生—针灸推拿学]