葛根芩连汤及其拆方配伍FTIR图谱比较研究  

Study on FTIR Spectrum's Compatibility with Different Prescriptions of Gegen Qinlian Decoction

作　　者：任蕾[1] 孙伟卫 李亚妮[1] 王颖莉[1] 宋强[1] 

机构地区：[1]山西中医学院中药学院,山西太原030024

出　　处：《辽宁中医杂志》2015年第4期830-834,共5页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金资助项目(81273659)

摘　　要：目的:利用FTIR(傅里叶变换红外光谱)技术研究葛根芩连汤中不同配伍时葛根素的溶出变化。方法:对葛根芩连汤中药物的加减、提取﹑浓缩成浸膏,利用FTIR技术进行分析得到11组数据,利用OMNIC软件的图谱加减功能来进行图谱加减,根据吸收峰的强弱推断其药效。结果:黄连有抑制黄芩素溶出的效果,而黄芩可帮助黄连药效提高。全方配伍时有效出峰最强最多。结论:利用FTIR技术可以进行葛根芩连汤配伍机理的研究。Objective：By using FTIR（Fourier transform infrared spectroscopy） technique to study puerarin extract of different compatibilities of Gegen Qinlian Decoction.Methods：The components extracts of Gegen Qinlian Decoction were obtained and 11 sets of data were studied by FTIR technology.According to the absorption peaks of the OMNIC software,its pesticide effect was studied.Results：Rhizoma coptidis can inhibit the effect of radix scutellariae＇s dissolution and radix scutellariae can improve pesticide effect.Full compatibility of Gegen Qinlian Decoction can get the most effective and strongest peak.Conclusion：FTIR technology can greatly improve the research on the prescription mechanism of Gegen Qinlian Decoction.

关 键 词：葛根芩连汤 FTIR指纹表征 葛根素 

分 类 号：R284.2[医药卫生—中药学]