子宫外发生异位葡萄胎3例临床病理分析及文献复习  

Clinicopathological Features of 3 Cases of Ectopic Hydatid Mole and Literature Review

作　　者：宗豫蓉 胡永斌[2] 

机构地区：[1]中信湘雅生殖与遗传专科医院生殖中心,湖南长沙410008 [2]中南大学湘雅基础医学院病理学系,湖南长沙410008

出　　处：《医学临床研究》2015年第3期443-445,449,共4页Journal of Clinical Research

摘　　要：【目的】探讨子宫外异位葡萄胎的临床病理特点及免疫表型。【方法】回顾性分析3例子宫外异位葡萄胎的临床病理资料，并辅以免疫组化标记p57、p53和Ki67。【结果】2例病变部位在右输卵管、1例在阴蒂；2例诊断为部分性葡萄胎，1例为侵蚀性葡萄胎；免疫组化：3例p57均阳性表达，侵蚀性葡萄胎病例p53和Ki67表达强度明显强于部分性葡萄胎。【结论】子宫外异位葡萄胎少见，好发部位在输卵管，绝大部分为部分性葡萄胎，p57、p53和Ki67对葡萄胎的病理诊断有重要参考价值。[Objective]To explore the clinicopathological characteristics and immunophenotype of ectopic hydatid mole .[Methods] Three cases of ectopic hydatid mole were retrospectively analyzed .And p57 ,p53 and Ki67 were detected by immunochemistry .And the relevant literature was reviewed .[Results]The lesion sites were right ovarian duct （ n =2） and cauda muliebris （ n =1） .And the diagnoses were partial hydatidi‐form mole （ n=2） and invasive hydatidiform mole （ n=1） .All 3 cases were all positive for p57 .The expres‐sions of p53 and Ki67 were obviously stronger in invasive hydatidiform mole （case 3） than those in partial hy‐datidiform （cases 1＆amp;2） .[Conclusion] Ectopic hydatid mole is rare and its predilection site occurs at ovarian duct .Most of them belong to partial hydatidiform mole .And p57 ,p53 and Ki67 are helpful for pathological diagnosis of hydatidiform mole .

关 键 词：葡萄胎/病理学 妊娠  异位 免疫表型分型 

分 类 号：R714.22[医药卫生—妇产科学]