A new strategy to improve the sensitivity and selectivity of dopamine detection  

作　　者：Xiang Xie Jing Gu Wenbo Zhao Shujuan Liu Yonghui Qiao Xinyu Zhu Xiaohong Yin Zhiwei Zhu Meixian Li Yuanhua Shao 

机构地区：[1]Institute of Nuclear Chemistry and Physics, China Academy of Engineering Physics [2]Beijing National Laboratory for Molecular Sciences [3]College of Chemistry and Molecular Engineering,Peking University

出　　处：《Science China Chemistry》2015年第5期892-898,共7页中国科学（化学英文版）

基　　金：financially supported by the National Natural Science Foundation of China(21335001,21075004)

摘　　要：We applied the combination of in situ electrochemical liquid-phase microextraction and square-wave voltammetric stripping analysis for the first time as a highly sensitive and selective approach for the detection of dopamine. A mixed gel of graphene sheets and an ionic liquid of 1-octyl-3-methylimidazolium hexaflurophosphate(OMim PF6) was used as a micro liquid-phase to pre-concentrate dopamine by controlled potential electrolysis from an aqueous solution(as a donor phase), followed by square-wave voltammetric stripping detection. Under optimized conditions, a linear calibration curve was obtained in the range of 0.05 to 1.0 ?mol/L in the presence of excess ascorbic acid and uric acid. The detection limit has been found to be 8.0 nmol/L(S/N=3).We applied the combination of in situ electrochemical liquid-phase microextraction and square-wave voltammetric stripping analysis for the first time as a highly sensitive and selective approach for the detection of dopamine. A mixed gel of graphene sheets and an ionic liquid of 1-octyl-3-methylimidazolium hexaflurophosphate （OMimPF6） was used as a micro liquid-phase to pre-concentrate dopamine by controlled potential electrolysis from an aqueous solution （as a donor phase）, followed by square-wave voltammetric stripping detection. Under optimized conditions, a linear calibration curve was obtained in the range of 0.05 to 1.0 μmol/L in the presence of excess ascorbic acid and uric acid. The detection limit has been found to be 8.0 nmol/L （S/N=3）.

关 键 词：dopamine detection graphene/OMimPF6 gel-modified electrode electrochemical microextraction square-wavevoltammetric stripping 

分 类 号：O657[理学—分析化学]