2型糖尿病患者口服药物治疗现况分析  

Analysis of the current situation of oral drug treatment of patients with type 2 diabetes

作　　者：刘湘茹[1] 杨斌[2] 胡德龙[1] 

机构地区：[1]广东省佛山市顺德第一人民医院内分泌科,广东佛山528300 [2]广东省佛山市顺德第一人民医院内分泌科血液风湿科,广东佛山528300

出　　处：《中国当代医药》2015年第11期150-152,共3页China Modern Medicine

基　　金：广东省佛山市卫生局医学科研立项(2011478)

摘　　要：目的分析顺德地区2型糖尿病患者口服药物治疗的血糖控制情况,并分析不良影响因素,为本地区2型糖尿病的防治工作提供必要参考。方法 2010年9月~2012年12月,选择顺德地区2型糖尿病患者进行研究,以调查问卷方式收集其基本资料,分别将Hb A1c≤6.5%及Hb A1c〈7%作为血糖控制达标标准,比较不同年龄、病程、文化程度、治疗方案等患者的血糖控制达标率,并对血糖达标的影响因素进行Logistic回归分析。结果总达标人数为126例,占63.00%,未达标74例,占37.00%;≥70岁患者的未达标率为56.25%,显著高于〈70岁患者的27.94%;病程〉10年患者的未达标率为72.41%,显著高于〈5年、5~10年的21.95%、39.33%;未接受教育患者的未达标率更高,占43.59%,显著高于受过高等教育的13.64%;3种药物联合使用的未达标率为68.42%,显著高于单药及2种药物联合的43.68%、24.47%（P〈0.05）;Logistic回归结果分析显示,年龄、联合用药时间、合理饮食、运动、教育与否是影响血糖达标的独立危险因素。结论顺德地区2型糖尿病患者口服药物的血糖达标率有待提高,影响达标率的主要因素包括年龄、运动、饮食、受教育程度,上述因素需引起重视。Objective To analyze the blood glucose control of oral drug treatment of patients with type 2 diabetes in Shunde area and analyze the adverse effect factors in order to provide the necessary reference for the prevention and treatment work of the type 2 diabetes in the region. Methods From September 2010 to December 2012,patients with type 2 diabetes in Shunde area were studied and the basic data was collected through questionnaire.Hb A1c≤6.5% and Hb A1c7% were respectively used as the blood glucose control standard criteria.The compliance rate of blood glucose control in patients of different age,the course of disease,degree of culture and treatment scheme were compared.The effect factor of blood glucose compliance was analyzed through Logistic regression analysis. Results The number of patients who reached the blood glucose control standard was 126 cases（63.00%）,but the patients who didn′t reach the blood glucose control standard were 74 cases（37.00%）.Non compliance rate of the patients over 70 years old（56.25%） was obviously higher than that of the patients below 70 years old（27.94%）（P〈0.05）.Non compliance rate of the patients with course of disease 10 years（72.41%） was obviously higher than that of course of disease 5 years and 5-10 years（21.95%,39.33% respectively）;higher non compliance rate of patients did not receive education（43.59%） was obviously higher than that of patients receiveing higher education（13.64%）;non compliance rate of combined use of the 3 drugs（68.42%） was significantly higher than that of single drug and combined use of 2 drugs（43.68%,24.47% respectively）（P〈0.05）.Logistic regression analysis showed that age,diet control,time of combined use of drug,a reasonable diet,exercise,education or not was the independent risk factors influencing blood glucose reaching the standard. Conclusion The compliance rate of blood glucose control in the patients with type 2 diabetes remains to be improved.The main factors affecting the compliance rate i

关 键 词：2型糖尿病 口服药物 现状 

分 类 号：R587.1[医药卫生—内分泌]