膝骨性关节炎的中医证候特点研究  

Research of TCM syndrome characteristics on knee osteoarthritis

作　　者：郭跃[1] 杨青梅[2] 鲁超[2] 方小燕[1] 刘道兵[2] 何海军[2] 赵铁军[2] 陈卫衡[2] 

机构地区：[1]贵阳中医学院,贵州贵阳550002 [2]中国中医科学院望京医院,北京100102

出　　处：《中医临床研究》2015年第4期1-4,共4页Clinical Journal Of Chinese Medicine

基　　金：国家自然科学基金资助项目(编号:81072900)

摘　　要：目的：探讨膝骨性关节炎的中医证候特点，为其临床辨证论治提供理论依据。方法：制定《膝骨性关节炎的中医证候信息量表》，收集2012年9月-2013年3月间就诊于中国中医科学院望京医院的217例膝骨性关节炎患者临床资料，进行聚类分析及主成分分析，归纳出证候分型以及各型的主次症。结果：出现频率80%以上的症状依次为固定痛、刺痛、活动后加重、隐痛、关节肿胀、冷痛、痛处拒按、屈伸不利；频率在60%-80%区间的10个症状中6个为全身表现：腰膝酸软、畏寒肢冷、变天加重、面肢浮肿、酸困无力、形体肥胖。聚类后血瘀气滞型、脾肾阳虚型、肝肾亏虚型三型分别占17.5%、48.3%、34.1%。结论：临床辨证分型需同时参照局部和全身证候表现。血瘀气滞型、脾肾阳虚型、肝肾亏虚型为临床常见证型，就诊时以脾肾阳虚型最常见。Objective： To investigate the characteristics of TCM syndrome on knee osteoarthritis, providing a theory basis for clinical differentiation and treatment. Methods： TCM syndrome scale of knee osteoarthritis was established, clinical information of 217 cases were collected in Wangjing hospital from March 2012 to September 2013, all cases received cluster and principal component analysis;TCM syndrome, primary symptoms and minor symptoms were summarized. Results： Frequency of symptoms was more than 80%, included fixed pain, twinge, the pain was increased after activity, dull pain, arthrocele, psychroalgia, the pain place was unpressable and the knee’s flexion and extension was limited. Between the frequency range of 60%-80%, 6 symptoms in 10 symptoms were general symptom, included soreness of loins and knees, aversion to cold, pain more at bad weather, puffiness of face and limbs, laziness and obesities. Xueyu Qizhi type accounted for 17.5%, Pishen Yangxu type accounted for 48.3%, Ganshen Kuixu type accounted for 34.1%by cluster analysis. Conclusion：Differentiation and classification of syndrome should rely on local and systemic symptoms. Xueyu Qizhi type, Pishen Yangxu type and Ganshen Kuixu type were common in clinic. Pishen Yangxu type was the most.

关 键 词：膝骨性关节炎 中医证候 聚类分析 主成分分析 

分 类 号：R593.22[医药卫生—内科学]