补气化痰活血方治疗进展性缺血性卒中临床观察  

Clinical observation on treating progressive ischemic stroke with the Buqi Huatan Huoxue recipe

作　　者：李向荣[1] 付中应[1] 易宣超[1] 张鹏[1] 林旭明[1] 

机构地区：[1]湖南中医药大学第二附属医院,湖南长沙410005

出　　处：《中医临床研究》2015年第4期19-22,共4页Clinical Journal Of Chinese Medicine

摘　　要：目的：观察补气化痰活血方治疗进展性缺血性卒中（PIS）的疗效。方法：112例 PIS 患者随机分为治疗组和对照组，每组56例。在一般治疗的基础上，治疗组在病情进展发生后予补气化痰活血方中药汤剂口服，服1剂后如病情停止进展，不再服，如仍进展则次日再服1剂，最多服2剂。分别于入院时、入院后每天上午7：30，下午17：30各进行1次神经功能缺损评分（采用斯堪的那维亚卒中量表，SSS），共15d，并于入院时进行1次日常生活活动能力评分（采用Barthel指数，BI），以及发病后3个月随访时进行1次SSS和BI评分。结果：治疗组56例患者有50例于病情进展发生后第2d，3例于第3d，3例于第4-7d停止进展；而对照组56例患者有20例于第2d，25例于第3d，11例于第4-7d停止进展。两组比较有非常显著性差异（P〈0.01）。入院时治疗组SSS评分为（46.23±8.32）分，进展发生后第7d为（48.56±4.12）分，前后比较无显著性差异；入院时对照组SSS评分为（46.43±9.02）分，进展发生后第7d为（20.35±5.7）分，前后比较有非常显著性差异（P〈0.01），第7d时组间比较有非常显著性差异（P〈0.01）。发病后3个月时治疗组SSS、BI评分分别为（56.24±2.75）分、（98.34±7.64）分，与入院时比较无显著性差异；对照组 SSS、BI 评分分别为（37.67±8.12）分、（52.18±19.47）分，与入院时比较均有显著性差异（P〈0.05），组间比较均有显著性差异（P〈0.05）。结论：以白参为主药的补气化痰活血方可有效阻止PIS的进展，显著改善患者预后。Objective：To observe clinical efficacy of the Buqi Huatan Huoxue recipe on progressive ischemic stroke. Methods：112 patients were randomly divided into two groups, all were given routine treatment;the treatment group was given the Buqi Huatan Huoxue recipe more. Results：In treatment group, 50 cases ceased on the second day, 3 cases ceased on the third day, 3 cases ceased in section 4-7 days;in the control, 20 cases ceased on the second day, 25 cases ceased on the third day, 11 cases ceased in section 4-7 days, the difference was statistically significant （P〈0.01）. At admission, SSS scores in the treatment group was （46.23±8.32） points, it was （48.56±4.12） points at the seventh day after the progression, there was no significant difference; SSS scores in the control group was （46.43±9.02） points, it was （20.35±5.7） points at the seventh day after the progression, the difference was statistically significant （P〈0.01）. The difference of SSS scores in two groups was statistically significant （P〈0.01）. After 3 months of onset SSS and BI scores in the treatment group were （56.24±2.75） points and （98.34±7.64） points, without significantly difference;in the control group, those were （37.67±8.12） points and （52.18±19.47） points, with significantly difference （P〈0.05）. Conclusion： The Buqi Huatan Huoxue recipe can effectively prevent the progress of PIS and significantly improve prognosis.

关 键 词：补气化痰活血 进展性缺血性卒中 

分 类 号：R255.2[医药卫生—中医内科学]