酮咯酸氨丁三醇联合山莨菪碱治疗肾绞痛的疗效观察  

Effect of ketorolac tromethamine and anisodamine in treatment of renal colic

作　　者：王剑[1] 吕广欣 聂屾[1] 杨龙[1] 冯加彬 刘东明[1] 

机构地区：[1]河北省沧州市中心医院急诊科,061001

出　　处：《临床合理用药杂志》2015年第12期17-18,共2页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的探讨酮咯酸氨丁三醇联合山莨菪碱治疗肾绞痛的疗效。方法选取2011—2013年沧州市中心医院急诊科收治的肾绞痛患者457例,随机分为治疗组(228例)与对照组(229例)。治疗组患者予以酮咯酸氨丁三醇联合山莨菪碱治疗,对照组患者予以盐酸哌替啶联合山莨菪碱治疗。观察两组患者临床疗效及不良反应(如恶心、呕吐、头晕、尿潴留、低血压、过敏等)发生情况。结果两组患者总有效率比较,差异无统计学意义(P>0.05);治疗组患者不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论酮咯酸氨丁三醇联合山莨菪碱治疗肾绞痛的疗效显著,且不良反应少,安全性高。Objective To explore the effect of ketorolac tromethamine and anisodamin in treatment of renal colic.Methods A total of 457 patients with renal colic were selected in Cangzhou Central Hospital from 2011 to 2013,they were randomly divided into treatment group（ 228 cases） and control group（ 229 cases）. Traetment group was treated with ketorolac tromethamine and anisodamine,control group was treated with pethidine hydrochloride and anisodamine. Clinical effect and adverse reactions（ such as nausea, vomiting, dizziness, urinary retention, low blood pressure, allergies） between the two groups were compared. Results The total effective rate showed no significant differences between the two groups（ P 0. 05）,the adverse reactions rate of treatment group was lower than that of control group（ P 0. 05）. Conclusion Ketorolac tromethamine and anisodamine has notable curative effect in the treatment of renal colic,has less adverse reactions and high safety.

关 键 词：肾绞痛 酮咯酸氨丁三醇 山莨菪碱 治疗结果 

分 类 号：R691.4[医药卫生—泌尿科学]