肌钙蛋白、降钙素原对心脏术后感染性休克病情程度的预测价值  

Predictive Value of c Tn I and PCT in the Illness Degree of Infectious Shock After Cardiac Surgery

作　　者：余锋尤 杨普云[1] 吴全忠[1] 

机构地区：[1]广东省茂名市人民医院外科ICU,广东茂名518001

出　　处：《临床医学工程》2015年第4期457-458,共2页Clinical Medicine & Engineering

摘　　要：目的探讨肌钙蛋白(cTnI)、降钙素原(PCT)对心脏术后感染性休克病情程度的预测价值。方法根据是否合并感染性休克将我院重症监护室的106例心脏术后患者分为观察组(合并感染性休克,50例)和对照组(未合并感染性休克,56例)。采用免疫吸附试验法检测cTnI水平,免疫散射比浊法检测PCT水平,比较两组患者的cTnI和PCT水平。结果观察组cTnI和PCT水平分别为(5.64±1.05)μg/L和(1.95±0.31)ng/L,高于对照组的(0.72±3.12)μg/L和(0.28±0.15)ng/L,差异具有统计学意义(P<0.05)。感染性休克患者开始发病时的cTnI和PCT水平均明显高于治疗12h和治疗24h时,而且随着治疗时间的延长,cTnI和PCT水平也降低,差异均具有统计学意义(P<0.05)。结论肌钙蛋白和降钙素原对心脏术后感染性休克具有重要的诊断意义,对不同病情程度的感染性休克具有预测作用。Objective To study the predictive value of cardiac troponin （cTnI） and procalcitonin （PCT） in the illness degree of infectious shock after cardiac surgery. Methods 106 cases of patients after cardiac surgery in ICU were divided into observation group （complicating infectious shock, 50 cases） and control group （without infection, 56 cases） according to whether complicating infectious shock. The level of cTnI was detected by ELISA, the level of PCT was detected by immune nephelometry. The cTnI and PCT levels of two groups were compared. Results The level of cTnI and PCT in observation group were （5.64 ± 1.05） μg/L and （1.95 ± 0.31） ng/L respectively, higher than （0.72±3.12）μg/L and （0.28±0.15） ng/L in control group, with statistical difference （P〈0.05）. The level of cTnI and PCT of infectious shock patients at onset were higher than the level after 12 h and 24 h of treatment, and with the extension of treatment time, the cTnI and PCT were decreased, all the difference was statistical （P 〈0.05）. Conclusions cTnI and PCT have important diagnostic significance in infectious shock after cardiac surgery, and have predictive value in different illness degree of infectious shock.

关 键 词：肌钙蛋白 降钙素原 心脏手术 感染性休克 

分 类 号：R631.4[医药卫生—外科学]