经皮椎体成形术(PVP)治疗骨质疏松性椎体压缩性骨折的临床应用  

Clinical Application of Percutaneous Vertebroplasty(PVP) in the Treatment of Osteoporotic Vertebral Compression Fractures

作　　者：王广欣[1] 郭大伟[1] 马兆吉[2] 金家峰[3] 曹媛[4] 陈民[4] 

机构地区：[1]沈阳市第四人民医院,辽宁沈阳110000 [2]鞍山市中心医院,辽宁鞍山114001 [3]沈阳医学院附属中心医院,辽宁沈阳110000 [4]辽宁中医药大学,辽宁沈阳110078

出　　处：《现代生物医学进展》2015年第13期2483-2486,共4页Progress in Modern Biomedicine

基　　金：国家自然科学基金面上项目(30500720)

摘　　要：目的:研究经皮椎体成形术(PVP)治疗骨质疏松性椎体压缩性骨折的临床疗效。方法:选取我院骨科收治的骨质疏松性椎体压缩性骨折(OVCF)患者80例,并将其随机分为两组,其中保守治疗组40例,予卧硬板床、功能锻炼配合药物常规治疗;手术治疗组40例,予PVP手术配合药物治疗。观察比较治疗前后两组患者的疼痛评分(VAS)、活动能力评分、Cobb's角及椎体高度。结果:1治疗后,两组患者的VAS评分与治疗前相比均明显降低(P<0.05);治疗后1周,手术组的VAS评分与保守组比较,明显降低(P<0.05);2治疗后,两组患者的活动能力评分与治疗前相比均明显降低(P<0.05);治疗后1周,手术组活动能力评分与保守组比较明显降低(P<0.05);3治疗后1月,两组患者的Cobb's角与治疗前相比均明显减小(P<0.05),椎体高度均明显恢复,差异有统计学意义(P<0.05)。结论:采用经皮椎体成形术治疗骨质疏松性椎体压缩性骨折具有良好的临床疗效,值得深入研究。Objective： To study the clinical efficacy of pereutaneous vertebroplasty （PVP） in the treatment of osteoporotie vertebral compression fractures. Methods： 80 cases ofosteoporotic vertebral compression fracture （OVCF） admitted in our hospital were selected and randomly divided into two groups, 40 cases of the conservative treatment group were treated with hard bed, functional exercise and medication, while another 40 cases of the operation group were treated with drug and PVP. Then the visuai analogue scale （VAS）, activity rating scale, Cobb＇s angle and vertebral height were compared before and after treatment between two groups. Results： ①After treat ment, the VAS scores of two groups significantly decreased than before （P〈0.05）; When compared with the conservative group, the VAS score of operation group decreased significantly （P〈0.05）. ②After treatment, the activity score of two groups significantly decreased compared with those before treatment （P〈0.05）; at 1st week after treatment, compared with the conservative group, the activity score of operation group decreased siguifieantly（P〈0.05）; ③After treatment, the Cobb＇s angles of both groups significantly decreased when compared with before, and the vertebral height significantly restored （P〈0.05）. Conclusions： Percutaneous vertebroplasty had a good clinical efficacy in treatment of osteoporotic vertebral compression fractures, which was worthy of further study.

关 键 词：椎体压缩性骨折 骨质疏松 经皮椎体成形术 临床疗效 

分 类 号：R683.2[医药卫生—骨科学]