大直径陶瓷假体用于全髋关节置换术的稳定性和安全性  

Effect of Large Diameter Ceramic Prosthesis on Stability and Function of Hip Joint in Total Hip Arthroplasty in Patients with Osteonecrosis

作　　者：陈宪凯 孙新君[2] 张福田[2] 易会钧 高歌军[3] 

机构地区：[1]潍坊医学院,山东潍坊261000 [2]中国人民解放军第89医院,山东潍坊261000 [3]东南大学,江苏南京210096

出　　处：《现代生物医学进展》2015年第15期2875-2877,共3页Progress in Modern Biomedicine

基　　金：国家自然科学基金面上项目(30770625)

摘　　要：目的:探讨大直径陶瓷-陶瓷假体对髋关节置换患者术后假体磨损,稳定性和髋关节功能的影响。方法:选取我院2010年1月-2014年1月间采用大直径陶瓷-陶瓷假体行关全髋置换的股骨头坏死患者46例作为研究组。另选40例采用标准金属-聚乙烯假体手术患者作为对照组。观察并比较两组患者假体磨损情况、髋关节稳定性和功能评分。结果:研究组患者术后无一例脱位,发生假体松动1例,Harris评分为(82.04±1.92)分;对照组术后发生假体脱位4例,松动4例,Harris评分为(81.37±1.27)分;研究组假体稳定性和磨损程度优于对照组,差异具有统计学意义(P<0.05),但两组髋关节功能评分无显著差异(P>0.05)。发生假体松动的患者术后血沉、IL-1和IL-6浓度均高于正常值,差异具有统计学意义(P<0.05)。结论:与标准假体相比,大直径陶瓷-陶瓷假体稳定性好,磨损率低,是全髋置换手术的良好假体。Objective： To investigate the effects of large diameter ceramic prosthesis on the stability and function of hip joint in to- tal hip arthroplasty in patients with osteonecrosis. Methods： 46 cases with large diameter ceramic ceramic prosthesis in hip replacement patients with femoral head necrosis were selected in our hospital from January 2010 to 2014, and another 40 cases with standard prosthe- sis operation were selected as the control group. Then the stability and functional difference of the hip prosthesis between the two groups were compared. Results： The X-ray showed 1 cases of loosening of the prosthesis, and the score of postoperative Harris hip was （82.04±1.92）. For the standard prosthesis replacement group, there was 4 cases of dislocation after two years, 2 cases of loosening of the prosthe- sis, and Harris score of （81.37±1.27）. There was statistical significance in the stability and prosthetic wear degree between the two groups （P〈0.05）, but no significant differences in hip function （P〉0.05）. IL-1 and IL-6 concentration of patients with prosthetic loosening were significantly higher than those of the control group, and the blood sedimentation and CRP were higher than those of the control group with statistically significant differences （P〈0.05）. Conclusions： Compared with standard prosthesis, large diameter ceramic prosthe- sis has good stability, low wear rate, and can be used as total hip replacement.

关 键 词：陶瓷假体 股骨头坏死 全髋置换 稳定性 

分 类 号：R687.4[医药卫生—骨科学] R318.08[医药卫生—外科学]