红芪对油酸型肺损伤大鼠肺泡表面活性物质含量及板层小体的影响  

Effects of Radix Hedysari on Changes of Pulmonary Surfactant and Osmiophilic Multilamellar Body in Rats with Respiratory Distress Syndrome

作　　者：白娟[1] 黄正良[1] 李萍[1] 

机构地区：[1]甘肃中医学院

出　　处：《中药药理与临床》1997年第2期26-28,共3页Pharmacology and Clinics of Chinese Materia Medica

摘　　要：本文用油酸型大鼠呼吸窘迫综合征（ＲＤＳ）模型，研究了红芪水提物（ＨＥ）对其影响的机理。结果表明，ＨＥ能提高大鼠ＲＤＳ的肺泡表面活性物质（ＰＳ），电镜观察发现ＨＥ对大鼠ＲＤＳⅡ型肺泡细胞有保护作用，能促使其恢复产生和释放ＰＳ功能，稳定了细胞内板层小体的结构。The experimental research on effective mechanism of Radix Hedysari(HE) treated Respiratory Distress Syndrome (RDS) induced by oleic acid were observed. The results showed that HE could increase contents of pulmonary surfactant(PS) in RDS rats. The observed under electronic microscope found that HE could protect Ⅱ type alveolar cells, promote their function of producing and releasing PS recovered,and steady structure of osmiophilic multilamellar body in cells.

关 键 词：红芪 油酸型肺损伤 肺泡表面活性物质 板层小体 

分 类 号：R285.5[医药卫生—中药学]