新疆和田墨玉县维吾尔族女性HPV感染相关因素分析  

Factors analysis for HPV infection within Uyghur women in Moyu County Hotan Region

作　　者：张璐[1] 高洁[2] 古扎丽努尔.阿不力孜 李华[1] 帕提曼.米吉提 

机构地区：[1]新疆医科大学附属肿瘤医院妇外五科,乌鲁木齐830011 [2]新疆医科大学附属肿瘤医院体检中心,乌鲁木齐830011

出　　处：《新疆医科大学学报》2015年第4期394-399,共6页Journal of Xinjiang Medical University

基　　金：国家自然科学基金(81160247)

摘　　要：目的探讨新疆和田墨玉县维吾尔族农村女性人乳头状瘤病毒（human papilloma virus,HPV）感染现状及感染相关因素,为新疆地区子宫颈癌防治提供科学依据和指导。方法 2013年5月15日-11月15日在和田墨玉县选取墨玉镇、喀尔赛乡、奎雅乡、扎瓦乡、雅瓦乡的21~60岁维吾尔族有性生活女性6 000例,采用整群抽样的方法进行HPV检测及HPV感染相关因素的问卷调查,问卷内容包括基本信息、婚育状况、性行为等。由2名妇科医生采集标本并应用care HPV检测,以结果阳性判定为HPV感染,对数据进行统计学分析。结果共输入有效问卷6 000份,研究人群HPV总感染率为8.4%。HPV感染与年龄（χ2=15.835,P〈0.001）、婚姻状况（χ2=12.805,P〈0.001）、职业（χ2=15.540,P〈0.001）、文化程度（χ2=25.224,P〈0.001）、家庭收入（χ2=5.637,P〈0.05）有关。多因素Logistic回归分析显示：文化程度、同房频次与HPV感染存在关联（P〈0.05）。结论新疆和田地区墨玉县维吾尔族农村妇女的HPV感染与年龄、婚姻状况、职业、同房频次存在一定关联。应该针对相关高危因素制定相应措施,规范人群行为,加强45岁以上妇女的筛查,进行有效干预。Objective To investigate the current status of the Human Papilloma Virus （HPV）infection and the infection factors within rural Uyghur women in Moyu County,Hotan Region,and to provide quantita-tive support and guidance for the cervical cancer prevention in Xinjiang.Methods A survey on HPV tes-ting and HPV infection factors was conducted on a total of 6 000 Uyghur women with sexual activities aged 21 to 60 in Moyu,Dakar,Kuiya,Ayman al and Yawa of Moyu County,Hotan region,between June 15 and November 15,2013.Survey questions include basic information,obstetrical history,sexual activities. Specimens were collected by two gynecologists and positive CareHPV testing result was utilized to deter-mine HPV infection.EpiData was used to process raw data.Statistical analysis was conducted using SPSS 18.0.Chi-square test was used to test the differences in HPV infection rate and multivariate dichotomous. logistic regression analysis was conducted to evaluate the effects of different risk factors.Statistical signifi-cance was determined by （P ≤0.05）.Results A total of 6 000 valid questionnaire copies was considered in the study.The population overall infection rate was 8.42%.Chi-square test result suggests that HPV in-fection correlates with age （χ2 =22.529,P =0.002）,marital status （χ2 =13.970,P =0.001）,occupation （χ2 =21.157 P 〈0.001）,level of education （χ2 = 36.175,P 〈0.001）,annual household income （χ2 =11.621,P =0.009）,contraception situation （χ2 = 8.154,P =0.017）,age when getting married （χ2 =20.360,P 〈0.001）,number of marriages （χ2 = 11.605,P =0.003）,number of sexual activities （χ2 =60.126,P 〈0.001）.These factors are then incorporated into the multivariate logistic regression frame-work,Regression analysis shows that level of education,frequency of sexual activities,found correlated with HPV infection and are statistically significant （P 〈0.05）.Conclusion HPV infection among rural Uyghur women in Hotan region of Xinjiang is found correlated with age,mari

关 键 词：维吾尔族 农村 妇女 HPV感染 危险因素 

分 类 号：R395.6[哲学宗教—心理学]