早产低体重儿脑室周围白质损伤定量评价的临床指导意义  

Clinical significance of brain white matter damage quantitative evaluation for low birth weight premature

作　　者：赵少岚[1] 陈创鑫[1] 简惠娜[1] 

机构地区：[1]广东省汕头市妇幼保健院儿科,广东汕头515000

出　　处：《中国现代医生》2015年第10期40-42,共3页China Modern Doctor

基　　金：广东省汕头市医疗科技计划项目(汕府科[2013]88)

摘　　要：目的：探讨头颅B超灰度定量测定对早期发现早产低体重儿脑室周围白质损伤的临床指导意义。方法对2013年1月~2014年8月本院NICU收治100例早产低体重儿随机分为对照组及治疗组，运用头颅B超联合医学图像分析软件于生后72 h内对脑室周围白质进行灰度值测定，治疗组对早期白质灰度值＆gt;130者采用早期营养脑神经及康复治疗，并随访跟踪生后3个月、6个月神经生长发育。结果治疗组早产低体重儿NBNA评分明显高于对照组，随访跟踪3个月、6个月神经生长发育情况明显优于对照组，差异有统计学意义（P〈0.05）。结论头颅B超灰度定量分析对早产低体重儿脑室周围白质损伤早期诊断有重要指导意义，并有助于判断预后及指导临床早期治疗。Objective To investigate the clinical significance of the gray head B ultrasound quantitative determination on early detection for preterm low birth weight infants with cerebral white matter damage. Methods From 2013 January to August 2014 in the NICU department of our hospital, 100 cases of preterm and low birth weight infants were ran-domly divided into the treatment group and the control group. After birth 72 hours, the value of cerebral white matter was measured by head B ultrasound combined with medical image analysis software. The cases, whose early values of cerebral white matter were above 130, were treated with early brain nerve nutrition and rehabilitation. The develop-ment of nerve growth was followed up in 3 months and 6 months after birth, respectively. Results The NBNA score of premature and low birth weight infants was significantly higher than that of the control group. By the follow-up investi-gation in 3 months and 6 months after birth, the nerve growth of the treatment group was significantly better than that of the control group. Conclusion The head B ultrasound gray-scale quantitative analysis has important guiding signifi-cance for early diagnosis of premature and low birth weight infants with cerebral white matter injury,and it can help to judge the prognosis and guide early clinical treatment.

关 键 词：早产低体重儿 脑室周围白质损伤 头颅B超 灰度 

分 类 号：R722.1[医药卫生—儿科]