影响粉尘螨滴剂治疗过敏性鼻炎疗效的相关因素分析  

Related factors analysis of the effect of dust mites drops for the treatment of allergic rhinitis

作　　者：陈其国[1] 汪琼[1] 林世光[2] 李浩[1] 李小虎[1] 孙群[1] 李雪丽[3] 

机构地区：[1]深圳市宝安区石岩人民医院耳鼻咽喉科,深圳518108 [2]深圳市宝安区石岩人民医院儿科,深圳518108 [3]山东万杰医学院药学系,医药营销班山东淄博255213

出　　处：《中国当代医药》2015年第10期10-13,共4页China Modern Medicine

基　　金：广东省深圳市宝安区科技计划社会公益项目(2014253)

摘　　要：目的：探讨影响粉尘螨滴剂治疗过敏性鼻炎疗效的相关因素。方法采用回顾性方法分析2012年1月-2014年6月在本院门诊就诊的过敏原为尘螨的过敏性鼻炎患者326例，采用粉尘螨滴剂舌下含服脱敏治疗，根据患者鼻炎症状、体征进行评分，采用单因素及多因素方法进行统计学分析。结果年龄、多重过敏原、病程、对症药物治疗、规则用药、伴发鼻窦炎、疗程为粉尘螨滴剂治疗过敏性鼻炎疗效的影响因素（P〈0.05），年龄、规则用药、疗程是影响粉尘螨滴剂治疗过敏性鼻炎疗效的独立因素（P〈0.05）。结论应用粉尘螨滴剂治疗过敏性鼻炎应尽早、规则、足够疗程用药，同时对症治疗过敏性鼻炎、鼻窦炎等症状，均能提高脱敏治疗的效果。Objective To explore the related factors of the effect of dust mites drops for the treatment of allergic rhini-tis. Methods 326 patients with allergic rhinitis whose the allergen for dust mites from January 2012 to June 2014 in our hospital were retrospectively analysed,with the therapy of dust mites drops under the tongue administering desensi-tization.The effect was evaluated by the symptoms and signs.The single factor and multiple factors method was used for statistical analysis. Results Age,multiple allergens,duration,rules of drug therapy,medication,with sinusitis,period of treatment was the related factors to affect the treatment of allergic rhinitis （P〈0.05）.Age,rules of drug therapy,a course was independent factor to affect the treatment of allergic rhinitis （P〈0.05）. Conclusion The therapy of dust mites drops for treatment of allergic rhinitis should be early,ruled,and with enough courses.At the same time,the symptom such as those with allergic rhinitis,sinusitis should be treated properly,which can improve the effect of desensitization therapy.

关 键 词：粉尘螨滴剂 过敏性鼻炎 疗效 因素分析 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]