多囊卵巢综合征和代谢综合征的关系及其预防与治疗进展  

Progress of relationship,prophylaxis and therapy of polycystic ovary syndrome and metabolic syndrome

作　　者：田小英[1] 侯丽辉[2] 葛军 刘颖华[1] 

机构地区：[1]黑龙江中医药大学,哈尔滨150040 [2]黑龙江中医药大学附属第一医院妇产科,哈尔滨150040 [3]天津市滨海新区塘沽妇幼保健院,300452

出　　处：《中华妇幼临床医学杂志（电子版）》2015年第2期114-116,共3页Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition)

基　　金：国家中医药行业科研专项(201207001);国家中医药管理局国家中医临床研究基地业务建设科研专项课题(JDZX2012039)~~

摘　　要：多囊卵巢综合征(PCOS)是女性最常见的内分泌疾病,与肥胖、胰岛素抵抗(IR)和代谢综合征(MS)密切相关,而中心性肥胖和IR是MS的2个主要特点,因此PCOS和MS之间相互联系、相互影响。PCOS患者的MS发病率相对较高,而MS女性患者通常又表现为PCOS的生殖/内分泌特征,因此PCOS和MS在预防和治疗方面具有相似性,可通过对纠正个体肥胖及改善IR的治疗,以达到预防心血管疾病、2型糖尿病及改善PCOS年轻患者生殖功能障碍等目的。目前,对PCOS与MS二者的治疗主要涉及调整生活方式、药物治疗、减肥手术及针对PCOS为主的腹腔镜手术。Polycystic ovary syndrome（PCOS） is the most common endocrine disorders in females. PCOS is closely associated with obesity,insulin resistance（IR） and metabolic syndrome（MS）. Central obesity and IR are two main features of MS. The relationship between PCOS and MS is intercommunication and interaction： not only PCOS women have a higher prevalence of MS,but also MS women usually present the reproductive/endocrine traits of PCOS. PCOS and MS are similar in prevention and treatment. With the treatment of obesity and IR, we may prevent cardiovascular disease, type 2 diabetes and improve reproductive dysfunction in young PCOS females. Currently, main treatment of PCOS and MS involves lifestyle modification,medication,bariatric surgery and laparoscopic ovarian surgery for PCOS.

关 键 词：多囊卵巢综合征 代谢综合征 胰岛素抗药性 肥胖症 治疗 

分 类 号：R711.75[医药卫生—妇产科学]