甲硝唑治疗肠伤寒穿孔临床观察  

Clinical Observation of Metronidazole in Treatment of Intestinal Typhoid With Perforation

作　　者：周春辉 

机构地区：[1]黑龙江省鹤岗市红十字医院,154100

出　　处：《中国卫生标准管理》2015年第10期202-203,共2页China Health Standard Management

摘　　要：目的探讨甲硝唑治疗肠伤寒穿孔的临床效果。方法随机抽取我院2011年4月-2013年4月收治的肠伤寒穿孔患者120例为研究对象，并将其随机分成对照组和观察组，每组患者分别为60例，对照组患者采用常规治疗措施，观察组患者在常规治疗的基础上实行甲硝唑进行治疗。比较两组患者的临床治疗效果。结果治疗结果显示，观察组患者的治疗效果优于对照组患者。观察组患者中仅有15例患者发生了并发症，对照组患者有34例患者发生并发症，差异有统计学意义（P〈0.05）。同时，观察组患者的死亡率低于对照组患者，差异有统计学意义（P〈0.05）。结论在治疗肠伤寒穿孔的过程中，在基础治疗措施的同时，给予患者甲硝唑药物，不仅能够减少患者并发症的发生率，还能降低死亡率。Objective To study clinical effect of metronidazole in treatment of intestinal typhoid with perforation. Methods 120 patients with intestinal typhoid with perforation in our hospital from April 2011 to April 2013 were randomly selected into observation group and control group,60 patients in each group. The patients in control group received conventional treatment,on the basis of that,the observation group patients received metronidazole treatment. Results The therapeutic effect of observation group was significantly better than that in control group. Only 15 patients had complications in observation group,while 34 patients had complications in control group,the differences had statistical significance（P〈0.05）. At the same time, the death rate in observation group was lower than that in control group patients,the differences had statistical significance（P〈0.05）. Conclusion Metronidazole in treatment of intestinal typhoid with perforation on the basis of conventional treatment,can not only reduce the occurrence rate of complications,but also reduce the death rate.

关 键 词：甲硝唑 肠伤寒穿孔 临床观察 

分 类 号：R656.7[医药卫生—外科学]